Ερευνητικά | Τριανταλή Δήμητρα
Αρχική > Ερευνητικά
  • 2024
  • Chalkiadaki K., Statoulla E., Zafeiri M., Voudouri G., Amvrosiadis T., Typou A., Theodoridou N., Moschovas D., Avgeropoulos A., Samiotaki M., Mason J. O. and Gkogkas CG. (2024) GABA/Glutamate neuron differentiation imbalance and increased AKT/mTOR signalling in CNTNAP2-/- cerebral organoids. bioRxiv , https://doi.org/10.1101/2024.04.21.590378
  • Vrettos EΙ, Kyrkou SG, Zoi V, Giannakopoulou M, Chatziathanasiadou MV, Kanaki Z, Agalou A, Bistas VP, Kougioumtzi A, Karampelas T, Diamantis DA, Murphy C, Beis D, Klinakis A, Tamvakopoulos C, Kyritsis AP, Alexiou GA, Tzakos AG. (2024) A Novel Fluorescent Gemcitabine Prodrug That Follows a Nucleoside Transporter-Independent Internalization and Bears Enhanced Therapeutic Efficacy With Respect to Gemcitabine. Chemistry ,
  • 2023
  • Chalkiadaki K., Statoulla E., Zafeiri M., Haji N., Lacaille J.C., Powell C.M., Jafarnejad S.M., Khoutorsky A., Gkogkas C. G. (2023) Reversal of memory and autism-related phenotypes in Tsc2+/- mice via inhibition of Nlgn1. Front Cell Dev Biol , 10.3389/fcell.2023.1205112
  • 2022
  • O.D. Papagiannopoulos, C. Papaloukas, V.C. Pezoulas, H.J.G. van de Werken, C. Poulet, Y.M. Mueller, P.D. Katsikis, D. de Seny, D.I. Fotiadis (2022) "Comparison of Proteomic Assay Methods in Autoinflammatory Disease Classification" IEEE-EMBS International Conference on Biomedical and Health Informatics (BHI) ,
  • Vlachoyiannopoulos PG, Chatzis LG, Goules AV, Argyropoulou OD, Englezopoulou A, Stergiou I, Voulgarelis M, Tsanakas P, Exarchos T, Gorgoulis VV, Fotiadis DI, Tzioufas AG. (2022) Patient-centered approaches for patients with systemic autoimmune rheumatic diseases: development and evolution Expert Rev Clin Immunol. [Abstract],
  • Kostopoulou M, Ugarte-Gil MF, Pons-Estel B, van Vollenhoven RF, Bertsias G. (2022) The association between lupus serology and disease outcomes: A systematic literature review to inform the treat-to-target approach in systemic lupus erythematosus Lupus. [Abstract],
  • Ntali S, Nikolopoulos D, Pantazi L, Emmanouilidou E, Papagoras C, Fanouriakis A, Dimopoulou D, Kallitsakis I, Boki K, Dania V, Sidiropoulos PI, Boumpas DT, Bertsias G. (2022) Remission or low disease activity at pregnancy onset are linked to improved foetal outcomes in women with systemic lupus erythematosus: results from a prospective observational study Clin Exp Rheumatol. [Abstract],
  • Tsiomita S, Liveri EM, Vardaka P, Vogiatzi A, Skiadaresis A, Saridis G, Tsigkas I, Michaelidis TM, Mavrothalassitis G, Thyphronitis G. (2022) ETS2 repressor factor (ERF) is involved in T lymphocyte maturation acting as regulator of thymocyte lineage commitment J Leukoc Biol. [Abstract],
  • De Vita S, Isola M, Baldini C, Goules AV, Chatzis LG, Quartuccio L, Zabotti A, Giovannini I, Donati V, Ferro F, Rizzo MT, Manfrè V, Pegolo E, Voulgarelis M, Zaja F, Fanin R, Masaoutis C, Rontogianni D, Fotiadis DI, Ponzoni M, Tzioufas AG. (2022) Predicting lymphoma in Sjögren's syndrome and the pathogenetic role of parotid microenvironment through precise parotid swelling recording Rheumatology (Oxford). [Abstract],
  • Bitzogli K, Jahaj E, Bakasis AD, Kapsogeorgou EK, Goules AV, Stergiou I, Pezoulas V, Antoniadou C, Skendros P, Ritis K, Fotiadis DI, Kotanidou A, Tzioufas AG, Vlachoyiannopoulos PG. (2022) Incidence of autoantibodies related to systemic autoimmunity in patients with severe COVID-19 admitted to the intensive care unit Clin Exp Rheumatol. [Abstract],
  • Kotzampasi DM, Premeti K, Papafotika A, Syropoulou V, Christoforidis S, Cournia Z, Leondaritis G. (2022) The orchestrated signaling by PI3Kα and PTEN at the membrane interface Comput Struct Biotechnol J. [Abstract],
  • Chalkiadaki K, Hooshmandi M, Lach G, Statoulla E, Simbriger K, Amorim IS, Kouloulia S, Zafeiri M, Pothos P, Bonneil É, Gantois I, Popic J, Kim SH, Wong C, Cao R, Komiyama NH, Atlasi Y, Jafarnejad SM, Khoutorsky A, Gkogkas CG. (2022) Mnk1/2 kinases regulate memory and autism-related behaviours via Syngap1 Brain. [Abstract],
  • 2021
  • Kougioumtzi A, Chatziathanasiadou MV, Vrettos EI, Sayyad N, Sakka M, Stathopoulos P, Mantzaris MD, Ganai AM, Karpoormath R, Vartholomatos G, Tsikaris V, Lazarides T, Murphy C, Tzakos AG. (2021) Development of novel GnRH and Tat 48-60 based luminescent probes with enhanced cellular uptake and bioimaging profile Dalton Trans. [Abstract], 10.1039/D1DT00060H
  • Mincarone P, Bodini A, Sabina S, Colella R, Tumolo MR, Fawdry M, Fotiadis DI, Leo CG. (2021) Simulated versus physical bench tests: The economic evaluation of the InSilc platform for designing, developing, and assessing vascular scaffolds Medicine (Baltimore). [Abstract],
  • Akoumianaki T, Vaporidi K, Diamantaki E, Pène F, Beau R, Gresnigt MS, Gkountzinopulou M, Venichaki M, Drakos E, El-Benna J, Samonis G, Le KTT, Kumar V, Georgopoulos D, van de Veerdonk FL, Netea MG, Latge JP, Chamilos G. (2021) Uncoupling of IL-6 signaling and LC3-associated phagocytosis drives immunoparalysis during sepsis Cell Host Microbe. [Abstract],
  • Tsafas V, Giouroukou K, Kounakis K, Mari M, Fotakis C, Tavernarakis N, Filippidis G. (2021) Monitoring aging-associated structural alterations in Caenorhabditis elegans striated muscles via PSHG measurements J Biophotonics. [Abstract],
  • Statoulla E, Chalkiadaki K, Karozis D, Gkogkas CG. (2021) Regulation of mRNA translation in stem cells; links to brain disorders Cell Signal. [Abstract],
  • Chalkiadaki K, Statoulla E, Markou M, Bellou S, Bagli E, Fotsis T, Murphy C, Gkogkas CG. (2021) Translational control in neurovascular brain development R Soc Open Sci. [Abstract],
  • Georgakis S, Gkirtzimanaki K, Papadaki G, Gakiopoulou H, Drakos E, Eloranta ML, Makridakis M, Kontostathi G, Zoidakis J, Baira E, Rönnblom L, Boumpas DT, Sidiropoulos P, Verginis P, Bertsias G. (2021) NETs decorated with bioactive IL-33 infiltrate inflamed tissues and induce IFN-α production in patients with SLE JCI Insight. [Abstract],
  • Dionysopoulou M, Diallinas G. (2021) Impact of Membrane Lipids on UapA and AzgA Transporter Subcellular Localization and Activity in Aspergillus nidulans J Fungi (Basel). [Abstract],
  • Diallinas G. (2021) Transporter Specificity: A Tale of Loosened Elevator-Sliding Trends Biochem Sci. [Abstract],
  • Bertsias G. (2021) Dialogue: High-throughput studies in rheumatology: time for unsupervised clustering? Lupus Sci Med. [Abstract],
  • Vrettos EI, Karampelas T, Sayyad N, Kougioumtzi A, Syed N, Crook T, Murphy C, Tamvakopoulos C, Tzakos AG. (2021) Development of programmable gemcitabine-GnRH pro-drugs bearing linker controllable 'click' oxime bond tethers and preclinical evaluation against prostate cancer Eur J Med Chem. [Abstract],
  • Sakka MK, Riga M, Ioannidis P, Baliota GV, Tselika M, Jagadeesan R, Nayak MK, Vontas J, Athanassiou CG. (2021) Transcriptomic analysis of s-methoprene resistance in the lesser grain borer, Rhyzopertha dominica, and evaluation of piperonyl butoxide as a resistance breaker BMC Genomics. [Abstract],
  • Nikolopoulos D, Fanouriakis A, Bertsias G. (2021) Treatment of neuropsychiatric systemic lupus erythematosus: clinical challenges and future perspectives Expert Rev Clin Immunol. [Abstract],
  • Kourkoulou A, Zantza I, Foti K, Mikros E, Diallinas G. (2021) Context-dependent Cryptic Roles of Specific Residues in Substrate Selectivity of the UapA Purine Transporter J Mol Biol. [Abstract],
  • Gergianaki I, Garantziotis P, Adamichou C, Saridakis I, Spyrou G, Sidiropoulos P, Bertsias G. (2021) High Comorbidity Burden in Patients with SLE: Data from the Community-Based Lupus Registry of Crete J Clin Med. [Abstract],
  • Vogiatzi A, Baltsavia I, Dialynas E, Theodorou V, Zhou Y, Deligianni E, Iliopoulos I, Wilkie AOM, Twigg SRF, Mavrothalassitis G. (2021) Erf affects commitment and differentiation of osteoprogenitor cells in cranial sutures via the retinoic acid pathway Mol Cell Biol. [Abstract],
  • 2020
  • K. Kourou, V. Pezoulas, E. Georga, Th. Exarchos, C. Papaloukas, M. Voulgarelis, A. Goules, A. Nezos, A.G. Tzioufas, Η.M. Moutsopoulos, C. Mavragani, D.I. Fotiadis (2020) "Predicting Lymphoma Development by Exploiting Genetic Variants and Clinical Findings in a Machine Learning-Based Methodology With Ensemble Classifiers in a Cohort of Sjögren's Syndrome Patients" IEEE-EMBS International Conference on Biomedical and Health Informatics (BHI) ,
  • Charmpilas N, Ruckenstuhl C, Sica V, Büttner S, Habernig L, Dichtinger S, Madeo F, Tavernarakis N, Bravo-San Pedro JM, Kroemer G. (2020) Acyl-CoA-binding protein (ACBP): a phylogenetically conserved appetite stimulator Cell Death Dis. [Abstract],
  • Frangou E, Georgakis S, Bertsias G. (2020) Update on the cellular and molecular aspects of lupus nephritis Clin Immunol. [Abstract],
  • Kostopoulou M, Adamichou C, Bertsias G. (2020) An Update on the Diagnosis and Management of Lupus Nephritis Curr Rheumatol Rep. [Abstract],
  • Simbriger K, Amorim IS, Lach G, Chalkiadaki K, Kouloulia S, Jafarnejad SM, Khoutorsky A and Gkogkas C. G. (2020) Uncovering memory-related gene expression in contextual fear conditioning using ribosome profiling. Prog Neurobiol , 10.1016/j.pneurobio.2020.101903.
  • Atlasi Y, Jafarnejad SM, Gkogkas C. G., Vermeulen M, Sonenberg N, Stunnenberg HG. (2020) The translational landscape of ground state pluripotency Nat Commun , 10.1038/s41467-020-15449-9
  • Bertsias G. (2020) Therapeutic targeting of JAKs: from hematology to rheumatology and from the first to the second generation of JAK inhibitors Mediterr J Rheumatol. [Abstract],
  • Duxbury Z, Wang S, MacKenzie CI, Tenthorey JL, Zhang X, Huh SU, Hu L, Hill L, Ngou PM, Ding P, Chen J, Ma Y, Guo H, Castel B, Moschou PN, Bernoux M, Dodds PN, Vance RE, Jones JDG. (2020) Induced proximity of a TIR signaling domain on a plant-mammalian NLR chimera activates defense in plants Proc Natl Acad Sci U S A. [Abstract],
  • Charova SN, Dölfors F, Holmquist L, Moschou PN, Dixelius C, Tzelepis G. (2020) The RsRlpA Effector Is a Protease Inhibitor Promoting Rhizoctonia solani Virulence through Suppression of the Hypersensitive Response Int J Mol Sci. [Abstract],
  • Nikoloudakis N, Pappi P, Markakis EA, Charova SN, Fanourakis D, Paschalidis K, Delis C, Tzortzakakis EA, Tsaniklidis G. (2020) Structural Diversity and Highly Specific Host-Pathogen Transcriptional Regulation of Defensin Genes Is Revealed in Tomato Int J Mol Sci. [Abstract],
  • Ntellas P, Mavroeidis L, Gkoura S, Gazouli I, Amylidi AL, Papadaki A, Zarkavelis G, Mauri D, Karpathiou G, Kolettas E, Batistatou A, Pentheroudakis G. (2020) Old Player-New Tricks: Non Angiogenic Effects of the VEGF/VEGFR Pathway in Cancer Cancers (Basel). [Abstract],
  • Tsiailanis AD, Renziehausen A, Kiriakidi S, Vrettos EI, Markopoulos GS, Sayyad N, Hirmiz B, Aguilar MI, Del Borgo MP, Kolettas E, Widdop RE, Mavromoustakos T, Crook T, Syed N, Tzakos AG. (2020) Enhancement of glioblastoma multiforme therapy through a novel Quercetin-Losartan hybrid Free Radic Biol Med. [Abstract],
  • Rémillard-Labrosse G, Dean NL, Allais A, Mihajlović AI, Jin SG, Son WY, Chung JT, Pansera M, Henderson S, Mahfoudh A, Steiner N, Agapitou K, Marangos P, Buckett W, Ligeti-Ruiter J, FitzHarris G. (2020) Human oocytes harboring damaged DNA can complete meiosis I Fertil Steril. [Abstract],
  • 2019
  • Chen G, Xie W, Nah J, Sauvat A, Liu P, Pietrocola F, Sica V, Carmona-Gutierrez D, Zimmermann A, Pendl T, Tadic J, Bergmann M, Hofer SJ, Domuz L, Lachkar S, Markaki M, Tavernarakis N, Sadoshima J, Madeo F, Kepp O, Kroemer G. (2019) 3,4-Dimethoxychalcone induces autophagy through activation of the transcription factors TFE3 and TFEB EMBO Mol Med. [Abstract],
  • Latgé JP, Chamilos G. (2019) Aspergillus fumigatus and Aspergillosis in 2019 Clin Microbiol Rev. [Abstract],
  • Nikolopoulos D, Adamichou C, Bertsias G. (2019) Suspected systemic rheumatic diseases in patients presenting with cytopenias Best Pract Res Clin Rheumatol. [Abstract],
  • Salataj E, Stathopoulou C, Hafþórsson RA, Nikolaou C, Spilianakis CG. (2019) Developmental conservation of microRNA gene localization at the nuclear periphery PLoS One. [Abstract],
  • Goules AV, Exarchos TP, Pezoulas VC, Kourou KD, Venetsanopoulou AI, De Vita S, Fotiadis DI, Tzioufas AG. (2019) Sjögren's syndrome towards precision medicine: the challenge of harmonisation and integration of cohorts Clin Exp Rheumatol. [Abstract],
  • Hoang HD, Graber TE, Jia JJ, Vaidya N, Gilchrist VH, Xiang X, Li W, Cowan KN, Gkogkas C. G., Jaramillo M, Jafarnejad SM, Alain T. (2019) Induction of an Alternative mRNA 5' Leader Enhances Translation of the Ciliopathy Gene Inpp5e and Resistance to Oncolytic Virus Infection. Cell Rep , 10.1016/j.celrep.2019.11.072
  • Kouloulia S, Hallin EI, Simbriger K, Amorim IS, Lach G, Amvrosiadis T, Chalkiadaki K, Kampaite A, Truong VT, Hooshmandi M, Jafarnejad SM, Skehel P, Kursula P, Khoutorsky A and Gkogkas C. G. (2019) Raptor-Mediated Proteasomal Degradation of Deamidated 4E-BP2 Regulates Postnatal Neuronal Translation and NF-κB Activity. Cell Rep , 10.1016/j.celrep.2019.11.023
  • Simbriger K, Amorim IS, Chalkiadaki K, Lach G, Jafarnejad SM, Khoutorsky A and Gkogkas C. G. (2019) Monitoring translation in synaptic fractions using a ribosome profiling strategy. J Neurosci Methods. , 10.1016/j.jneumeth.2019.108456
  • Voutsina A, Fragiadakis G.S, Gkouskou K, Alexandraki D. (2019) Synergy of Hir1, Ssn6 and Snf2 global regulators is the functional determinant of a Mac1 transcriptional switch in S. cerevisiae copper homeostasis Curr Genet. [Abstract],
  • Gergianaki I, Fanouriakis A, Adamichou C, Spyrou G, Mihalopoulos N, Kazadzis S, Chatzi L, Sidiropoulos P, Boumpas DT, Bertsias G. (2019) Is systemic lupus erythematosus different in urban versus rural living environment? Data from the Cretan Lupus Epidemiology and Surveillance Registry Lupus. [Abstract],
  • Vogiatzi A, Mavrothalassitis G. (2019) Craniofacial, orofacial and dental disorders: the role of the RAS/ERK pathway Expert Rev Mol Med. [Abstract],
  • Papadakakis A, Sidiropoulou K, Panagis G. (2019) Music exposure attenuates anxiety- and depression-like behaviors and increases hippocampal spine density in male rats Behav Brain Res. [Abstract],
  • Stathopoulou C, Nikoleri D, Bertsias G. (2019) Immunometabolism: an overview and therapeutic prospects in autoimmune diseases Immunotherapy. [Abstract],
  • 2018
  • Amorim IS, Lach G and Gkogkas CG. (2018) The Role of the Eukaryotic Translation Initiation Factor 4E (eIF4E) in Neuropsychiatric Disorders. Front Genet. , 10.3389/fgene.2018.00561
  • Uttam, S., Wong, C, Amorim, I. S., Jafarnejad, S. M., Tansley, S., Yang, J., Prager-Khoutorsky, M., Mogil, J. S., Gkogkas, C. G.* and Khoutorsky, A.* (2018) Translational profiling of dorsal root ganglia and spinal cord in a mouse model of neuropathic pain. Neurobiology of pain , 10.1016/j.ynpai.2018.04.001
  • Amorim I.S., Kedia S., Kouloulia S., Simbriger K., Gantois I., Jafarnejad S. M., Li Y., Kampaite A., Pooters T., Romanò N and Gkogkas C. G. (2018) Loss of eIF4E phosphorylation engenders depression-like behaviors via selective mRNA translation. The Journal of neuroscience : the official journal of the Society for Neuroscience 21 , 10.1523/JNEUROSCI.2673-17.2018
  • Jafarnejad, S. M., Chapat, C., Matta-Camacho, E., Gelbart, I. A., Hesketh, G. G., Arguello, M., Garzia, A., Kim, S. H., Attig, J., Shapiro, M., Morita, M., Khoutorsky, A., Alain, T., Gkogkas, C., Stern-Ginossar, N., Tuschl, T., Gingras, A. C., Duchaine, T (2018) Translational control of ERK signaling through miRNA/4EHP-directed silencing. Elife 7 , 10.7554/eLife.35034
  • Rieckher M, Psycharakis Daniele Ancora SE, Liapis E, Zacharopoulos A, Ripoll J, Tavernarakis N, Zacharakis G. (2018) Demonstrating Improved Multiple Transport-Mean-Free-Path Imaging Capabilities of Light Sheet Microscopy in the Quantification of Fluorescence Dynamics Biotechnol J. [Abstract],
  • Pietrocola F, Castoldi F, Markaki M, Lachkar S, Chen G, Enot DP, Durand S, Bossut N, Tong M, Malik SA, Loos F, Dupont N, Mariño G, Abdelkader N, Madeo F, Maiuri MC, Kroemer R, Codogno P, Sadoshima J, Tavernarakis N, Kroemer G. (2018) Aspirin Recapitulates Features of Caloric Restriction Cell Rep. [Abstract],
  • 2017
  • Vorgia E, Zaragkoulias A, Peraki I, Mavrothalassitis G. (2017) Suppression of Fgf2 by ETS2 repressor factor (ERF) is required for chorionic trophoblast differentiation Mol Reprod Dev. [Abstract],
  • Martzoukou O, Amillis S, Zervakou A, Christoforidis S, Diallinas G. (2017) The AP-2 complex has a specialized clathrin-independent role in apical endocytosis and polar growth in fungi Elife. [Abstract], 10.7554/eLife.20083.
  • Chatzi KE., Sardis MF., Tsirigotaki A., Koukaki M., Šoštarić N., Konijnenberg A., Sobott F., Kalodimos CG., Karamanou S., Economou A. (2017) Preprotein mature domains contain translocase targeting signals that are essential for secretion J Cell Biol. [Abstract],
  • Peraki I, Palis J, Mavrothalassitis G. (2017) The Ets2 Repressor Factor (Erf) Is Required for Effective Primitive and Definitive Hematopoiesis Mol Cell Biol. [Abstract],
  • Martin, L. J., Smith, S. B., Khoutorsky, A., Magnussen, C. A., Samoshkin, A., Sorge, R. E., Cho, C., Yosefpour, N., Sivaselvachandran, S., Tohyama, S., Cole, T., Khuong, T. M., Mir, E., Gibson, D. G., Wieskopf, J. S., Sotocinal, S. G., Austin, J. S., Meloto, C. B., Gitt, J. H., Gkogkas, C., Sonenberg, N., Greenspan, J. D., Fillingim, R. B., Ohrbach, R., Slade, G. D., Knott, C., Dubner, R., Nackley, A. G., Ribeiro-da-Silva, A., Neely, G. G., Maixner, W., Zaykin, D. V., Mogil, J. S. & Diatchenko, L. (2017) Epiregulin and EGFR interactions are involved in pain processing. J Clin Invest 127 , 10.1172/JCI87406
  • Moy, J. K., Khoutorsky, A., Asiedu, M. N., Black, B. J., Kuhn, J. L., Barragan-Iglesias, P., Megat, S., Burton, M. D., Burgos-Vega, C. C., Melemedjian, O. K., Boitano, S., Vagner, J., Gkogkas, C. G., Pancrazio, J. J., Mogil, J. S., Dussor, G., Sonenberg, (2017) he MNK-eIF4E Signaling Axis Contributes to Injury-Induced Nociceptive Plasticity and the Development of Chronic Pain. The Journal of neuroscience : the official journal of the Society for Neuroscience 37 , 10.1523/JNEUROSCI.0220-17.2017
  • Gantois, I., Khoutorsky, A., Popic, J., Aguilar-Valles, A., Freemantle, E., Cao, R., Sharma, V., Pooters, T., Nagpal, A., Skalecka, A., Truong, V. T., Wiebe, S., Groves, I. A., Jafarnejad, S. M., Chapat, C., McCullagh, E. A., Gamache, K., Nader, K., Lacaille, J. C., Gkogkas, C. G.* & Sonenberg, N.* (2017) Metformin ameliorates core deficits in a mouse model of fragile X syndrome. Nature medicine 23 , 10.1038/nm.4335
  • Tuttle, A. H., Tansley, S., Dossett, K., Tohyama, S., Khoutorsky, A., Maldonado-Bouchard, S., Stein, L., Gerstein, L., Crawhall-Duk, H., Pearl, R., Sukosd, M., Leger, P., Hardt, O. M., Yachnin, D., Austin, J. S., Chan, C. M., Pooters, T., Groves, I., Martin, L. J., Sonenberg, N., Gkogkas, C. G.* & Mogil, J. S.* (2017) Social propinquity in rodents as measured by tube cooccupancy differs between inbred and outbred genotypes. Proceedings of the National Academy of Sciences of the United States of America 114 , 10.1073/pnas.1703477114
  • Latgé JP, Beauvais A, Chamilos G. (2017) The Cell Wall of the Human Fungal Pathogen Aspergillus fumigatus: Biosynthesis, Organization, Immune Response, and Virulence Annu Rev Microbiol. [Abstract],
  • Chapat, C., Jafarnejad, S. M., Matta-Camacho, E., Hesketh, G. G., Gelbart, I. A., Attig, J., Gkogkas, C. G., Alain, T., Stern-Ginossar, N., Fabian, M. R., Gingras, A. C., Duchaine, T. F. & Sonenberg, N. (2017) Cap-binding protein 4EHP effects translation silencing by microRNAs. Proceedings of the National Academy of Sciences of the United States of America , 10.1073/pnas.1701488114
  • Koussis K, Goulielmaki E, Chalari A, Withers-Martinez C, Siden-Kiamos I, Matuschewski K, Loukeris TG. (2017) Targeted Deletion of a Plasmodium Site-2 Protease Impairs Life Cycle Progression in the Mammalian Host PLoS One. [Abstract],
  • Papadakis G., Friedt J., Eck M., Rabus D., Jobst G., Gizeli E. (2017) Optimized acoustic biochip integrated with microfluidics for biomarkers detection in molecular diagnostics Biomed Microdevices. [Abstract],
  • 2016
  • Vyrla D, Nikolaidis G, Oakley F, Perugorria MJ, Tsichlis PN, Mann DA, Eliopoulos AG. (2016) TPL2 Kinase Is a Crucial Signaling Factor and Mediator of NKT Effector Cytokine Expression in Immune-Mediated Liver Injury J Immunol. [Abstract],
  • Gkouskou KK, Ioannou M, Pavlopoulos GA, Georgila K, Siganou A, Nikolaidis G, Kanellis DC, Moore S, Papadakis KA, Kardassis D, Iliopoulos I, McDyer FA, Drakos E, Eliopoulos AG. (2016) Apolipoprotein A-I inhibits experimental colitis and colitis-propelled carcinogenesis Oncogene. [Abstract],
  • Favicchio R, Psycharakis S, Schönig K, Bartsch D, Mamalaki C, Papamatheakis J, Ripoll J, Zacharakis G. (2016) Quantitative performance characterization of three-dimensional noncontact fluorescence molecular tomography J Biomed Opt. [Abstract],
  • Papanastasiou M., Orfanoudaki G., Kountourakis N., Koukaki M., Sardis M.F., Aivaliotis M., Tsolis K.C., Karamanou S., Economou A. (2016) Rapid label-free quantitative analysis of the E. coli BL21(DE3) inner membrane proteome Proteomics. [Abstract],
  • Portaliou A.G., Tsolis K.C., Loos M.S., Zorzini V., Economou A. (2016) Type III Secretion: Building and Operating a Remarkable Nanomachine Trends Biochem Sci. [Abstract],
  • Hu R, Cancela J, Arredondo Waldmeyer MT, Cea G, Vlachopapadopoulou EA, Fotiadis DI, Fico G. (2016) OB CITY-Definition of a Family-Based Intervention for Childhood Obesity Supported by Information and Communication Technologies IEEE J Transl Eng Health Med. [Abstract],
  • Tahmasebi S., Jafarnejad S. M., Tam I. S., Gonatopoulos-Pournatzis T., Matta-Camacho E., Tsukumo Y., Yanagiya A., Li W., Atlasi Y., Caron M., Braunschweig U., Pearl D., Khoutorsky A., Gkogkas C. G., Nadon R., Bourque G., Yang X. J., Tian B., Stunnenberg H (2016) Control of embryonic stem cells self-renewal and differentiation via coordinated splicing and translation of YY2. PNAS , 10.1073/pnas.1615540113
  • Khoutorsky, A., Sorge R.E., Prager-Khoutorsky M., Pawlowski S. A., Longod G., Jafarnejad S. M., Tahmasebi S., Martin L., Pitchere M. H., Gkogkas C. G., Sharif-Naeinig R., Alfredo Ribeiro-da-Silvad A., Bourque C. W., Cerveroh F., Mogil J. S., & Sonenberg N (2016) eIF2alpha phosphorylation controls thermal nociception PNAS , 10.1073/pnas.1614047113
  • Akoumianaki T, Chamilos G. (2016) DAPK1 Keeps the Peace in Antifungal Inflammation Cell Host Microbe. [Abstract],
  • Poirazi, P., Belin, D., Gräff, J., Hanganu‐Opatz, I., and López‐Bendito, G. (2016) Balancing family with a successful career in neuroscience. Eur J Neurosci. 44(2):1797-803 [Abstract],
  • Bozelos, P., Stefanou, S.S., Bouloukakis, G., Melachrinos, C., Poirazi, P. (2016) REMOD: A Tool for Analyzing and Remodeling the Dendritic Architecture of Neural Cells Front Neuroanat. 9:156. [Abstract],
  • Gkouskou KK, Ioannou M, Pavlopoulos GA, Georgila K, Siganou A, Nikolaidis G, Kanellis DC, Moore S, Papadakis KA, Kardassis D, Iliopoulos I, McDyer FA, Drakos E, Eliopoulos AG. (2016) Apolipoprotein A-I inhibits experimental colitis and colitis-propelled carcinogenesis Oncogene. [Abstract],
  • Koumakis L, Kanterakis A, Kartsaki E, Chatzimina M, Zervakis M, Tsiknakis M, Vassou D, Kafetzopoulos D, Marias K, Moustakis V, Potamias G. (2016) MinePath: Mining for Phenotype Differential Sub-paths in Molecular Pathways PLoS Comput Biol. [Abstract],
  • Kaprou G., Papadakis G., Papageorgiou D., Kokkoris G., Papadopoulos V., Kefala I., Gizeli E., Tserepi A. (2016) Miniaturized devices for isothermal DNA amplification addressing DNA diagnostics Microsystem Technologies. [Abstract],
  • Gogolides E., Tserepi A., Jobst G., Friedt J., Rabus D., Dupuy B., Bilkova Z., Descroix S., Viovy J., Papadakis G., Gizeli E. (2016) Micro-Nano-Bio Diagnostic System for Food Pathogen Detection Revolutionizes Food Safety Management & Protects Consumers Health Stud Health Technol Inform. [Abstract],
  • Glajch KE, Ferraiuolo L, Mueller KA, Stopford MJ, Prabhkar V, Gravanis A, Shaw PJ, Sadri-Vakili G. (2016) MicroNeurotrophins Improve Survival in Motor Neuron-Astrocyte Co-Cultures but Do Not Improve Disease Phenotypes in a Mutant SOD1 Mouse Model of Amyotrophic Lateral Sclerosis PLoS One. [Abstract],
  • Kastania A., Tsougeni K., Papadakis G., Gizeli E., Kokkoris G., Tserepi A., Gogolides E. (2016) Plasma micro-nanotextured polymeric micromixer for DNA purification with high efficiency and dynamic range Anal Chim Acta. [Abstract],
  • Pantazis A., Konstantinidis G., Gizeli E. (2016) Study of the Effect of the Operating Frequency of a GaN Lamb Wave Device to Viscosity and Protein Sensing IEEE Sensors Journal. [Abstract],
  • 2015
  • Khoutorsky, A., Bonin, R. P., Sorge, R. E., Gkogkas, C. G., Pawlowski, S. A., Jafarnejad, S. M., Pitcher, M. H., Alain, T., Perez-Sanchez, J., Salter, E. W., Martin, L., Ribeiro-da-Silva, A., De Koninck, Y., Cervero, F., Mogil, J. S. & Sonenberg, N. (2015) Translational control of nociception via 4E-binding protein 1 Elife 4 , 10.7554/eLife.12002
  • Maity, S., Rah, S., Sonenberg, N., Gkogkas, C. G. & Nguyen, P. V. (2015) Norepinephrine triggers metaplasticity of LTP by increasing translation of specific mRNAs. Learn Mem 22 , 10.1101/lm.039222.115
  • Cao, R., Gkogkas, C. G., de Zavalia, N., Blum, I. D., Yanagiya, A., Tsukumo, Y., Xu, H., Lee, C., Storch, K. F., Liu, A. C., Amir, S. & Sonenberg, N. (2015) Light-regulated translational control of circadian behavior by eIF4E phosphorylation. Nature Neuroscience 18 , 10.1038/nn.4010
  • Aulas, A., Caron, G., Gkogkas, C. G., Mohamed, N. V., Destroismaisons, L., Sonenberg, N., Leclerc, N., Parker, J. A. & Vande Velde, C. (2015) G3BP1 promotes stress-induced RNA granule interactions to preserve polyadenylated mRNA. J Cell Biol 209 , 10.1083/jcb.201408092
  • Niso-Santano M, Bravo-San Pedro JM, Maiuri MC, Tavernarakis N, Cecconi F, Madeo F, Codogno P, Galluzzi L, Kroemer G. (2015) Novel inducers of BECN1-independent autophagy: cis-unsaturated fatty acids Autophagy. [Abstract],
  • Stratigi K, Kapsetaki M, Aivaliotis M, Town T, Flavell RA, Spilianakis CG. (2015) Spatial proximity of homologous alleles and long noncoding RNAs regulate a switch in allelic gene expression Proc Natl Acad Sci U S A. [Abstract],
  • Filiou MD, Soukupova M, Rewerts C, Webhofer C, Turck CW, Maccarrone G. (2015) Variability assessment of 15N metabolic labeling-based proteomics workflow in mouse brain and plasma. Mol Biosyst ,
  • 2014
  • Saio T, Guan X, Rossi P, Economou A, Kalodimos CG. (2014) Structural basis for protein antiaggregation activity of the trigger factor chaperone Science. [Abstract],
  • Goulielmaki E, Sidén-Kiamos I, Loukeris TG. (2014) Functional Characterization of Anopheles Matrix Metalloprotease 1 Reveals Its Agonistic Role during Sporogonic Development of Malaria Parasites Infect Immun. [Abstract],
  • Liljenfeldt L, Gkirtzimanaki K, Vyrla D, Svensson E, Loskog AS, Eliopoulos AG. (2014) Enhanced therapeutic anti-tumor immunity induced by co-administration of 5-fluorouracil and adenovirus expressing CD40 ligand Cancer Immunol Immunother. [Abstract],
  • Gkouskou KK, Deligianni C, Tsatsanis C, Eliopoulos AG. (2014) The gut microbiota in mouse models of inflammatory bowel disease Front Cell Infect Microbiol. [Abstract],
  • Gkogkas, C. G., Khoutorsky, A., Cao, R., Jafarnejad, S. M., Prager-Khoutorsky, M., Giannakas, N., Kaminari, A., Fragkouli, A., Nader, K., Price, T. J., Konicek, B. W., Graff, J. R., Tzinia, A. K., Lacaille, J. C. & Sonenberg, N. (2014) Pharmacogenetic inhibition of eIF4E-dependent Mmp9 mRNA translation reverses fragile X syndrome-like phenotypes Cell reports 9 , 10.1016/j.celrep.2014.10.064
  • Jung, H., Gkogkas, C. G., Sonenberg, N. & Holt, C. E. (2014) Remote control of gene function by local translation. Cell 157 , 10.1016/j.cell.2014.03.005
  • Tahmasebi, S., Alain, T., Rajasekhar, V. K., Zhang, J. P., Prager-Khoutorsky, M., Khoutorsky, A., Dogan, Y., Gkogkas, C. G., Petroulakis, E., Sylvestre, A., Ghorbani, M., Assadian, S., Yamanaka, Y., Vinagolu-Baur, J. R., Teodoro, J. G., Kim, K., Yang, X. J. & Sonenberg, N. (2014) Multifaceted regulation of somatic cell reprogramming by mRNA translational control. Cell Stem Cell 14 , 10.1016/j.stem.2014.02.005
  • Primikyri A, Chatziathanasiadou MV, Karali E, Kostaras E, Mantzaris MD, Hatzimichael E, Shin JS, Chi SW, Briasoulis E, Kolettas E, Gerothanassis IP, Tzakos AG. (2014) Direct binding of Bcl-2 family proteins by quercetin triggers its pro-apoptotic activity ACS Chem Biol. [Abstract],
  • 2013
  • Balomenou S, Fouet A, Tzanodaskalaki M, Couture-Tosi E, Bouriotis V, Boneca IG. (2013) Distinct functions of polysaccharide deacetylases in cell shape, neutral polysaccharide synthesis and virulence of Bacillus anthracis Mol Microbiol. [Abstract],
  • Chen L, Ai X, Portaliou AG, Minetti CA, Remeta DP, Economou A, Kalodimos CG. (2013) Substrate-activated conformational switch on chaperones encodes a targeting signal in type III secretion Cell Rep. [Abstract],
  • Gkirtzimanaki K, Gkouskou KK, Oleksiewicz U, Nikolaidis G, Vyrla D, Liontos M, Pelekanou V, Kanellis DC, Evangelou K, Stathopoulos EN, Field JK, Tsichlis PN, Gorgoulis V, Liloglou T, Eliopoulos AG. (2013) TPL2 kinase is a suppressor of lung carcinogenesis Proc Natl Acad Sci U S A. [Abstract],
  • Kyrmizi I, Gresnigt MS, Akoumianaki T, Samonis G, Sidiropoulos P, Boumpas D, Netea MG, van de Veerdonk FL, Kontoyiannis DP, Chamilos G. (2013) Corticosteroids block autophagy protein recruitment in Aspergillus fumigatus phagosomes via targeting dectin-1/Syk kinase signaling J Immunol. [Abstract],
  • Gkogkas, C. G. & Sonenberg, N. (2013) Translational control and autism-like behaviors. Cell Logist 3 , 10.4161/cl.24551
  • Miliara S, Gkouskou KK, Sharp TV, Eliopoulos AG. (2013) SUMOylation is required for optimal TRAF3 signaling capacity PLoS One. [Abstract],
  • Khoutorsky, A., Gkogkas, C. G.*, Yanagiya, A.*, Fabian, M. R., Prager-Khoutorsky, M., Cao, R., Gamache, K., Bouthiette, F., Parsyan, A., Sorge, R. E., Mogil, J. S., Nader, K., Lacaille, J. C. & Sonenberg, N. (2013) Control of synaptic plasticity and memory via suppression of poly(A)-binding protein. Control of synaptic plasticity and memory via suppression of poly(A)-binding protein. , 10.1016/j.neuron.2013.02.025
  • Ran, I., Gkogkas, C. G., Vasuta, C., Tartas, M., Khoutorsky, A., Laplante, I., Parsyan, A., Nevarko, T., Sonenberg, N. & Lacaille, J. C. (2013) Selective regulation of GluA subunit synthesis and AMPA receptor-mediated synaptic function and plasticity by the translation repressor 4E-BP2 in hippocampal pyramidal cells. The Journal of neuroscience : the official journal of the Society for Neuroscience 33 , 10.1523/JNEUROSCI.3264-12.2013
  • Gkogkas, C. G., Khoutorsky, A., Ran, I., Rampakakis, E., Nevarko, T., Weatherill, D. B., Vasuta, C., Yee, S., Truitt, M., Dallaire, P., Major, F., Lasko, P., Ruggero, D., Nader, K., Lacaille, J. C. & Sonenberg, N. (2013) Autism-related deficits via dysregulated eIF4E-dependent translational control. Nature 493 , 10.1038/nature11628
  • 2012
  • Tripoliti EE, Fotiadis DI, Manis G. (2012) Automated diagnosis of diseases based on classification: dynamic determination of the number of trees in random forests algorithm IEEE Trans Inf Technol Biomed. [Abstract],
  • Chua, J. J., Schob, C., Rehbein, M., Gkogkas, C. G., Richter, D. & Kindler, S. (2012) Synthesis of two SAPAP3 isoforms from a single mRNA is mediated via alternative translational initiation. Sci Rep 2 , 10.1038/srep00484
  • Johnson MA, Tsai L, Roy DS, Valenzuela DH, Mosley C, Magklara A, Lomvardas S, Liberles SD, Barnea G. (2012) Neurons expressing trace amine-associated receptors project to discrete glomeruli and constitute an olfactory subsystem. Proc Natl Acad Sci U S A. ,
  • 2011
  • Sideridou M, Zakopoulou R, Evangelou K, Liontos M, Kotsinas A, Rampakakis E, Gagos S, Kahata K, Grabusic K, Gkouskou K, Trougakos IP, Kolettas E, Georgakilas AG, Volarevic S, Eliopoulos AG, Zannis-Hadjopoulos M, Moustakas A, Gorgoulis VG. (2011) Cdc6 expression represses E-cadherin transcription and activates adjacent replication origins J Cell Biol. [Abstract],
  • 2010
  • Kalousi A, Mylonis I, Politou AS, Chachami G, Paraskeva E, Simos G. (2010) Casein kinase 1 regulates human hypoxia-inducible factor HIF-1 J Cell Sci. [Abstract],
  • Tripoliti EE, Fotiadis DI, Argyropoulou M, Manis G. (2010) A six stage approach for the diagnosis of the Alzheimer's disease based on fMRI data J Biomed Inform. [Abstract],
  • Sigala F, Savvari P, Liontos M, Sigalas P, Pateras IS, Papalampros A, Basdra EK, Kolettas E, Papavassiliou AG, Gorgoulis VG. (2010) Increased expression of bFGF is associated with carotid atherosclerotic plaques instability engaging the NF-κB pathway J Cell Mol Med. [Abstract],
  • 2007
  • Apostolova, G., Dorn, R., Ka, S., Hallbook, F., Lundeberg, J., Liser, K., Hakim, V., Brodski, C., Michaelidis, T. M., and Dechant, G. (2007) Neurotransmitter phenotype-specific expression changes in developing sympathetic neurons. Mol. Cell. Neurosci. ,
  • 2004
  • Carroll J, FitzHarris G, Marangos P, Hallet G. (2004) Ca2+ signalling and cortical re-organisation during the transition from meiosis to mitosis in mammalian oocytes. Eur J Obstet Gynecol Reprod Biol. 115 Suppl 1 ,
  • P.F. Foltopoulou, G.A. Zachariadis, A.S. Politou, A.S. Tsiftsoglou and L.C. Papadopoulou (2004) Recombinant human wild-type and mutated forms of the mitochondrial Cox assembly Sco2 protein differ in physical state and copper binding capacity Mol. Genet. Metab. ,
  • Roussou I, Lambropoulos I, Pagoulatos GN, Fotsis T, Roussis IG. (2004) Decrease of heat shock protein levels and cell populations by wine phenolic extracts J Agric Food Chem. [Abstract],
  • Mearini, G., Nielsen, P.E., and Fackelmayer, F.O. (2004) Localization and Dynamics of Plasmid DNA in Live Mammalian Nuclei. Nucleic Acids Res. ,
  • 2003
  • Gkogkas, C. G.*, Vernikos, G. S.*, Promponas, V. J. & Hamodrakas, S. J. (2003) GeneViTo: visualizing gene-product functional and structural features in genomic datasets. BMC Bioinformatics 4 , 10.1186/1471-2105-4-53
  • Marangos P. FitzHarris G. and Carroll J (2003) Ca2+ oscillations at fertilization in mammals are regulated by the formation of pronuclei Development 130 ,
  • 2000
  • Almeida, O. F. X., G. L. Condé, C. Crochemore, B. A. Demeneix, D. Fischer, A. H. S. Hassan, M. Meyer, F. Holsboer, and T. M. Michaelidis. (2000) Subtle shifts in the ratio between pro- and anti-apoptotic molecules following activation of corticosteroid receptors decide neuronal fate. FASEB J. ,
  • 1998
  • G. I. Gallicano*, P. Kouklis*, C. Bauer, M. Yin, V. Vasioukhin, L. Degenstein, and E. Fuchs. (1998) Desmoplakin is required early in development for stabilization of desmosomes and cytoskeletal linkage. J. Cell Biol. 143 ,
  • Boot-Handford, R. P., T. M. Michaelidis, M. C. Hillarby, A. Zambelli, J. Denton, J. A. Hoyland, A. J. Freemont, M. E. Grant, and G. A. Wallis. (1998) he bcl-2 knockout mouse exhibits marked changes in osteoblast phenotype and collagen deposition in bone as well as a mild growth plate phenotype. Int. J. Exp. Pathology ,
  • 1996
  • Tzimagiorgis, G., T. M. Michaelidis, D. Lindholm, and H. Thoenen. (1996) Introduction of the negative selection marker into replacement vectors by a single ligation step Nucleic Acids Res. ,
  • 1995
  • Pipili-Synetos, E., Papageorgiou, A., Sakkoula, E., Sotiropoulou, G., Fotsis, T., Karakiulakis, G., and Maragoudakis, M.E. (1995) Inhibition of angiogenesis, tumour growth and metastasis by the NO-releasing vasodilators, isosorbide mononitrate and dinitrate. Br. J. Pharmacol. ,
  • Pipili-Synetos, E., Papageorgiou, A., Sakkoula, E., Sotiropoulou, G., Fotsis, T., Karakiulakis, G., and Maragoudakis, M.E. (1995) Inhibition of angiogenesis, tumour growth and metastasis by the NO-releasing vasodilators, isosorbide mononitrate and dinitrate. Br. J. Pharmacol. ,
  • Lonning, P.E., Helle, S-I., Johannessen, D.C., Adlerctreutz, H., Lien, E.A., Tally, M., Ekse, D., Fotsis, T., Anker, G.B., and Hall, K. (1995) Relations between sex hormones, sex hormone binding globulin, insulin-like growth factor-1 and insulin-like growth factor binding protein-1 in post-menopausal breasr cancer patients. Clinical Endocrinology ,
  • 1993
  • Johannessen, G. C, Adlerceutz, H., Fotsis, T., and Lonning, E. (1993) Plasma and urinary oestrogens in breast cancer patients on treatmnet with 4-hydroxyandrostenedione. Brit. J. Cancer ,
  • Adlercreutz, H., Fotsis, T., Lampe, J., Wähälä, K., Mäkelä, T., Brunow, G., and Hase, T. (1993) Quantitative determination of lignans and isoflavonoids in plasma of omnivorous and vegetarian women by isotope dilution gas chromatography-mass spectrometry. Scand. J. Clin. Lab. Invest. ,
  • Fotsis, T., Pepper, M., Adlercreutz, H., Fleischmann, G., Hase, T., Montesano, R. and Schweigerer, L. (1993) Genistein, a dietary-derived inhibitor of in vitro angiogenesis. Proc. Natl. Acad. Sci. ,
  • Michaelidis, T. M., G. Tzimagiorgis, N. Moschonas, and J. Papamatheakis. (1993) The human glutamate dehydrogenase gene family: gene organization and structural characterization. Genomics ,
  • 1992
  • Schweigerer, L., Christeleit, K., Fleischmann, G., Adlercreutz, H., Wähälä, K., Hase, T., Schwab, M., Ludwig, R., and Fotsis, T. (1992) Identification in human urine of a natural growth inhibitor for cells derived from solid pediatric tumours. Eur. J. Clin. Invest. ,
  • 1991
  • Adlercreutz, H., Fotsis, T., Bannwart, C., Wähälä, K., Brunow, G., and Hase, T. (1991) Isotope dilution gas chromatographic-mass spectrometric method for the determination of lignans and isoflavonoids in human urine, including identification of genistein. Clin. Chem. Acta. ,
  • 1986
  • Adlercreutz, H., Fotsis, T., Bannwart, C., Wähälä, K., Mäkelä, T., Brunow, G., and Hase, T. (1986) Determination of urinary lignans and phytoestrogen metabolites, potential antiestrogens and anticarcinogens,in urine of women on various habitual diets. J. Steroid Biochem. ,
  • Adlercreutz, H., Musey, P.I., Fotsis, T., Bannwart, C.,Wähälä, K., Mäkelä, T., Brunow, G., and Hase, T. (1986) Identification of lignans and phytoestrogens in urine of chimpanzees. Clin. Chim. Acta ,
  • 1984
  • Bannwart, C., Adlercreutz, H., Fotsis, T., Wähälä, K., Hase, T., and Brunow, G. (1984) Identification of O-desmethylangolesin, a metabolite of daidzein, and of metairesinol, one likely plant precursor of the animal lignan enterolactone, in human urine. Finn. Chem. Lett. ,