2018
- Patounas O, Papacharalampous I, Eckerich C, Markopoulos GS, Kolettas E, Fackelmayer FO. (2018) A novel splicing isoform of protein arginine methyltransferase 1 (PRMT1) that lacks the dimerization arm and correlates with cellular malignancy J Cell Biochem. [Abstract],
2017
- Markopoulos GS, Roupakia E, Tokamani M, Vartholomatos G, Tzavaras T, Hatziapostolou M, Fackelmayer FO, Sandaltzopoulos R, Polytarchou C, Kolettas E. (2017) Senescence-associated microRNAs target cell cycle regulatory genes in normal human lung fibroblasts Exp Gerontol. [Abstract],
2016
- Kolpa HJ, Fackelmayer FO, Lawrence JB. (2016) SAF-A Requirement in Anchoring XIST RNA to Chromatin Varies in Transformed and Primary Cells. Dev Cell. 2016 Oct 10; ,
2015
- Scaramuzzino C, Casci I, Parodi S, Lievens PM, Polanco MJ, Milioto C, Chivet M, Monaghan J, Mishra A, Badders N, Aggarwal T, Grunseich C, Sambataro F, Basso M, Fackelmayer FO, Taylor JP, Pandey UB, Pennuto M. (2015) Protein arginine methyltransferase 6 enhances polyglutamine-expanded androgen receptor function and toxicity in spinal and bulbar muscular atrophy Neuron. [Abstract],
2014
- Hall LL, Carone DM, Gomez AV, Kolpa HJ, Byron M, Mehta N, Fackelmayer FO, Lawrence JB. (2014) Stable C0T-1 repeat RNA is abundant and is associated with euchromatic interphase chromosomes Cell. [Abstract],
- Suchánková J, Legartová S, Sehnalová P, Kozubek S, Valente S, Labella D, Mai A, Eckerich C, Fackelmayer FO, Sorokin DV, Bartova E. (2014) PRMT1 arginine methyltransferase accumulates in cytoplasmic bodies that respond to selective inhibition and DNA damage Eur J Histochem. [Abstract],
2013
- Scaramuzzino C, Monaghan J, Milioto C, Lanson NA Jr, Maltare A, Aggarwal T, Casci I, Fackelmayer FO, Pennuto M, Pandey UB. (2013) Protein arginine methyltransferase 1 and 8 interact with FUS to modify its sub-cellular distribution and toxicity in vitro and in vivo PLoS One. [Abstract],
2009
- Herrmann F, Pably P, Eckerich C, Bedford MT, Fackelmayer FO. (2009) Human protein arginine methyltransferases in vivo--distinct properties of eight canonical members of the PRMT family J Cell Sci. [Abstract],
- Herrmann F, Fackelmayer FO. (2009) Nucleo-cytoplasmic shuttling of protein arginine methyltransferase 1 (PRMT1) requires enzymatic activity Genes Cells. [Abstract],
2008
- Malyavantham KS, Bhattacharya S, Barbeitos M, Mukherjee L, Xu J, Fackelmayer FO, Berezney R. (2008) Identifying functional neighborhoods within the cell nucleus: proximity analysis of early S-phase replicating chromatin domains to sites of transcription, RNA polymerase II, HP1gamma, matrin 3 and SAF-A J Cell Biochem. [Abstract],
2006
- Mearini G, Fackelmayer FO. (2006) Local chromatin mobility is independent of transcriptional activity Cell Cycle. [Abstract],
2005
- Fackelmayer FO. (2005) Protein arginine methyltransferases: guardians of the Arg? Trends Biochem Sci. [Abstract],
- Herrmann F, Lee J, Bedford MT, Fackelmayer FO. (2005) Dynamics of human protein arginine methyltransferase 1(PRMT1) in vivo J Biol Chem. [Abstract],
- Herrmann F, Fackelmayer FO. (2005) Nuclear architecture - on higher ground. A report on the Third Elmau Conference on Nuclear Organization: from Basic Science to Application Chromosome Res. [Abstract],
- Fackelmayer FO. (2005) A stable proteinaceous structure in the territory of inactive X chromosomes J Biol Chem. [Abstract],
2004
- Fackelmayer FO. (2004) Nuclear architecture and gene expression in the quest for novel therapeutics Curr Pharm Des. [Abstract],
- Herrmann F, Bossert M, Schwander A, Akgün E, Fackelmayer FO. (2004) Arginine methylation of scaffold attachment factor A by heterogeneous nuclear ribonucleoprotein particle-associated PRMT1 J Biol Chem. [Abstract],
- Jenke AC, Stehle IM, Herrmann F, Eisenberger T, Baiker A, Bode J, Fackelmayer FO, Lipps HJ. (2004) Nuclear scaffold/matrix attached region modules linked to a transcription unit are sufficient for replication and maintenance of a mammalian episome Proc Natl Acad Sci U S A. [Abstract],
- Mearini G, Nielsen PE, Fackelmayer FO. (2004) Localization and dynamics of small circular DNA in live mammalian nuclei Nucleic Acids Res. [Abstract],
- Mearini, G., Nielsen, P.E., and Fackelmayer, F.O. (2004) Localization and Dynamics of Plasmid DNA in Live Mammalian Nuclei. Nucleic Acids Res. ,
- Fackelmayer, F.O. (2004) Nuclear Architecture and Transcription Factors in the Quest for New Therapeutics. ,
2003
- Helbig, R. and Fackelmayer, F.O. (2003) Scaffold Attachment Factor A (SAF-A) is Concentrated in Inactive X Chromosome Territories Through its RGG Domain. Chromosoma ,
2002
- Jenke BH, Fetzer CP, Stehle IM, Jönsson F, Fackelmayer FO, Conradt H, Bode J, Lipps HJ. (2002) An episomally replicating vector binds to the nuclear matrix protein SAF-A in vivo EMBO Rep. [Abstract],
2001
- Eggert H, Schulz M, Fackelmayer FO, Renkawitz R, Eggert M. (2001) Effects of the heterogeneous nuclear ribonucleoprotein U (hnRNP U/SAF-A) on glucocorticoid-dependent transcription in vivo J Steroid Biochem Mol Biol. [Abstract],
- Kappes F, Burger K, Baack M, Fackelmayer FO, Gruss C. (2001) Subcellular localization of the human proto-oncogene protein DEK J Biol Chem. [Abstract],
- Jahr S, Hentze H, Englisch S, Hardt D, Fackelmayer FO, Hesch RD, Knippers R. (2001) DNA fragments in the blood plasma of cancer patients: quantitations and evidence for their origin from apoptotic and necrotic cells Cancer Res. [Abstract],
- Eckerich, C., Fackelmayer, F. O., and Knippers, R. (2001) Zinc affects the conformation of nucleoprotein filaments formed by replication protein A (RPA) and long natural DNA molecules Biochim Biophys Acta ,
2000
- Kipp, M., Schwab, B. L., Przybylski, M., Nicotera, P., and Fackelmayer, F. O. (2000) Apoptotic cleavage of scaffold attachment factor A (SAF-A) by caspase-3 occurs at a noncanonical cleavage site J Biol Chem ,
- Kipp, M., Göhring, F., Ostendorp, T., van Drunen, C. M., van Driel, R., Przybylski, M., and Fackelmayer, F. O. (2000) SAF-Box, a Conserved Protein Domain That Specifically Recognizes Scaffold Attachment Region DNA Mol Cell Biol ,
- Kreitz, S., Fackelmayer, F. O., Gerdes, J., and Knippers, R. (2000) The proliferation-specific human Ki-67 protein is a constituent of compact chromatin Exp Cell Res ,
- Fackelmayer, F. O. (2000) Die Architektur des Zellkerns BioSpektrum ,
1999
- Martelli, A.M., Bortul, R., Fackelmayer, F.O., Tazzari, P.L., Bareggi, R., Narducci, P. & Zweyer, M. (1999) Biochemical and morphological characterization of the nuclear matrix from apoptotic HL-60 cells. J Cell Biochem ,
- Treuner, K., Okuyama, A., Knippers, R. & Fackelmayer, F.O. (1999) Hyperphosphorylation of replication protein A middle subunit (RPA32) in apoptosis. Nucleic Acids Res ,
1998
- Nayler, O., Strätling, W., Bourquin, J.P., Stagljar, I., Lindemann, L., Jasper, H., Hartmann, A.M., Fackelmayer, F.O., Ullrich, A. & Stamm, S. (1998) SAF-B protein couples transcription and pre-mRNA splicing to SAR/MAR elements Nucleic Acids Res ,
1997
- Eggert, M., Michel, J., Schneider, S., Bornfleth, H., Baniahmad, A., Fackelmayer, F.O., Schmidt, S. & Renkawitz, R. (1997) The glucocorticoid receptor is associated with the RNA-binding nuclear matrix protein hnRNP U J Biol Chem ,
- Göhring, F. & Fackelmayer, F.O. (1997) he scaffold/matrix attachment region binding protein hnRNP-U (SAF-A) is directly bound to chromosomal DNA in vivo: a chemical cross-linking study. Biochemistry ,
- Göhring, F., Schwab, B.L., Nicotera, P., Leist, M. & Fackelmayer, F.O. (1997) The novel SAR-binding domain of scaffold attachment factor A (SAF-A) is a target in apoptotic nuclear breakdown. EMBO J. ,
- Ladenburger, E.M., Fackelmayer, F.O., Hameister, H. & Knippers, R (1997) MCM4 and PRKDC, human genes encoding proteins MCM4 and DNA-PKcs, are close neighbours located on chromosome 8q12-->q13. Cytogenet Cell Genet ,
- Neri, L.M., Fackelmayer, F.O., Zweyer, M., Kohwi-Shigematsu, T. & Martelli, A.M. (1997) Subnuclear localization of S/MAR-binding proteins is differently affected by in vitro stabilization with heat or Cu2+ Chromosoma ,
- Zweyer, M., Riederer, B.M., Ochs, R.L., Fackelmayer, F.O., Kohwi-Shigematsu, T., Bareggi, R., Narducci, P. & Martelli, A.M. (1997) Association of nuclear matrix proteins with granular and threaded nuclear bodies in cell lines undergoing apoptosis. Exp Cell Res ,
1996
- Renz, A. & Fackelmayer, F.O. (1996) Purification and molecular cloning of the scaffold attachment factor B (SAF-B), a novel human nuclear protein that specifically binds to S/MAR-DNA. Nucleic Acids Res. ,
1994
- Fackelmayer, F.O., Dahm, K., Renz, A., Ramsperger, U. & Richter, A. (1994) Nucleic-acid-binding properties of hnRNP-U/SAF-A, a nuclear-matrix protein which binds DNA and RNA in vivo and in vitro. Eur. J. Biochem ,
- Fackelmayer, F.O. & Richter, A. (1994) Purification of two isoforms of hnRNP-U and characterization of their nucleic acid binding activity. Biochemistry ,
- Fackelmayer, F.O. & Richter, A. (1994) hnRNP-U/SAF-A is encoded by two differentially polyadenylated mRNAs in human cells. Biochim. Biophys. Acta ,
- Romig, H., Ruff, J., Fackelmayer, F.O., Patil, M.S. & Richter, A. (1994) Characterisation of two intronic nuclear-matrix-attachment regions in the human DNA topoisomerase I gene. Eur. J. Biochem. ,
1992
- Romig, H., Fackelmayer, F.O., Renz, A., Ramsperger, U. & Richter, A. (1992) Characterization of SAF-A, a novel nuclear DNA binding protein from HeLa cells with high affinity for nuclear matrix/scaffold attachment DNA elements. EMBO J. ,
