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Research | Theodore Fotsis
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  • 2022
  • Chalmantzi V, Simitzi C, Papadopoulos A, Bagli E, Murphy C, Stratakis E, Fotsis T. (2022) Culturing Human Pluripotent Stem Cells on Micropatterned Silicon Surfaces Methods Mol Biol. [Abstract],
  • 2021
  • Papadopoulos A, Chalmantzi V, Mikhaylichenko O, Hyvönen M, Stellas D, Kanhere A, Heath J, Cunningham DL, Fotsis T, Murphy C. (2021) Combined transcriptomics and phosphoproteomic analysis of BMP4 signaling in human embryonic stem cells. Stem Cell Res. ,
  • Kostopoulou N, Bellou S, Bagli E, Markou M, Kostaras E, Hyvönen M, Kalaidzidis Y, Papadopoulos A, Chalmantzi V, Kyrkou A, Panopoulou E, Fotsis T, Murphy C. (2021) Embryonic stem cells are devoid of macropinocytosis, a trafficking pathway for activin a in differentiated cells J Cell Sci. [Abstract], 10.1242/jcs.246892
  • Chalkiadaki K, Statoulla E, Markou M, Bellou S, Bagli E, Fotsis T, Murphy C, Gkogkas CG. (2021) Translational control in neurovascular brain development R Soc Open Sci. [Abstract],
  • Papadopoulos A, Chalmantzi V, Hyvönen M, Stellas D, Syrrou M, Fotsis T, Murphy C. (2021) Supporting data on combined transcriptomic and phosphoproteomic analysis of BMP4 signaling in human embryonic stem cells Data Brief. [Abstract],
  • Xydias D, Ziakas G, Psilodimitrakopoulos S, Lemonis A, Bagli E, Fotsis T, Gravanis A, Tzeranis DS, Stratakis E. (2021) Three-dimensional characterization of collagen remodeling in cell-seeded collagen scaffolds via polarization second harmonic generation Biomed Opt Express. [Abstract],
  • Markou M, Kouroupis D, Fotsis T, Bagli E, Murphy C. (2021) Basic concepts in 3D Cell Culture. Book chapter: Vascularisation in 3D Cell Culture. [Abstract], 10.1007/978-3-030-66749-8
  • Papadopoulos A, Chalmantzi V, Mikhaylichenko O, Hyvönen M, Stellas D, Kanhere A, Heath J, Cunningham DL, Fotsis T, Murphy C (2021) upporting data on combined transcriptomics and phosphoproteomic analysis of BMP4 signaling in human embryonic stem cells. Data in Brief 35 ,
  • 2020
  • Markou M, Kouroupis D, Badounas F, Katsouras A, Kyrkou A, Fotsis T, Murphy C, Bagli E. (2020) Tissue Engineering Using Vascular Organoids From Human Pluripotent Stem Cell Derived Mural Cell Phenotypes Front Bioeng Biotechnol. [Abstract], 10.3389/fbioe.2020.00278.
  • Papadopoulos A, Chalmantzi V, Mikhaylichenko O, Hyvönen M, Stellas D, Kanhere A, Heath J, Cunningham DL, Fotsis T, Murphy C. (2020) Combined transcriptomic and phosphoproteomic analysis of BMP4 signaling in human embryonic stem cells Stem Cell Res. [Abstract],
  • Markou M, Kouroupis D, Badounas F, Katsouras A, Kyrkou A, Fotsis T, Murphy C, Bagli E. (2020) Tissue Engineering Using Vascular Organoids From Human Pluripotent Stem Cell Derived Mural Cell Phenotypes. Frontiers in Bioengineering and Biotechnology , 10.3389/fbioe.2020.00278
  • 2018
  • Kolettis TM, Bagli E, Barka E, Kouroupis D, Kontonika M, Vilaeti AD, Markou M, Roumpi M, Maltabe V, La Rocca V, Agathopoulos S, Fotsis T. (2018) Medium-term Electrophysiologic Effects of a Cellularized Scaffold Implanted in Rats After Myocardial Infarction Cureus. [Abstract],
  • 2017
  • Vlaikou AM, Kouroupis D, Sgourou A, Markopoulos GS, Bagli E, Markou M, Papadopoulou Z, Fotsis T, Nakos G, Lekka ME, Syrrou M. (2017) Mechanical stress affects methylation pattern of GNAS isoforms and osteogenic differentiation of hAT-MSCs Biochim Biophys Acta. [Abstract],
  • 2016
  • Basagiannis D, Zografou S, Murphy C, Fotsis T, Morbidelli L, Ziche M, Bleck C, Mercer J, Christoforidis S. (2016) VEGF induces signalling and angiogenesis by directing VEGFR2 internalisation through macropinocytosis J Cell Sci. [Abstract],
  • Tsolis K.C., Bagli E., Kanaki K., Zografou S., Carpentier S., Bei E.S., Christoforidis S., Zervakis M., Murphy C., Fotsis T., Economou A. (2016) Proteome Changes during Transition from Human Embryonic to Vascular Progenitor Cells J Proteome Res. [Abstract], 10.1021/acs.jproteome.6b00180.
  • Kyrkou A, Stellas D, Syrrou M, Klinakis A, Fotsis T, Murphy C. (2016) Generation of human induced pluripotent stem cells in defined, feeder-free conditions Stem Cell Res. [Abstract],
  • Kouroupis D, Kyrkou A, Triantafyllidi E, Katsimpoulas M, Chalepakis G, Goussia A, Georgoulis A, Murphy C, Fotsis T. (2016) Generation of stem cell-based bioartificial anterior cruciate ligament (ACL) grafts for effective ACL rupture repair Stem Cell Res. [Abstract],
  • Mantzaris MD, Bellou S, Skiada V, Kitsati N, Fotsis T, Galaris D. (2016) Intracellular labile iron determines H2O2-induced apoptotic signaling via sustained activation of ASK1/JNK-p38 axis Free Radic Biol Med. [Abstract],
  • Kyrkou A, Stellas D, Syrrou M, Klinakis A, Fotsis T, Murphy C (2016) Generation of human induced pluripotent stem cells in defined, feeder-free conditions. Stem Cell Research ,
  • 2015
  • Sanchez-Duffhues G, Fotsis T, ten Dijke P. (2015) Signal Transduction: Gain of Activin Turns Muscle into Bone. Curr Biol. ,
  • Yang J, AlTahan AM, Hu D, Wang Y, Cheng PH, Morton CL, Qu C, Nathwani AC, Shohet JM, Fotsis T, Koster J, Versteeg R, Okada H, Harris AL, Davidoff AM. (2015) The role of histone demethylase KDM4B in Myc signaling in neuroblastoma J Natl Cancer Inst. [Abstract],
  • 2014
  • Karali E, Bellou S, Stellas D, Klinakis A, Murphy C, Fotsis T. (2014) VEGF Signals through ATF6 and PERK to promote endothelial cell survival and angiogenesis in the absence of ER stress Mol Cell. [Abstract],
  • Kostaras E, Pedersen NM, Stenmark H, Fotsis T, Murphy C. (2014) SARA and RNF11 at the crossroads of EGFR signaling and trafficking Methods Enzymol. [Abstract],
  • Karali E, Bellou S, Stellas D, Klinakis A, Murphy C, Fotsis T. (2014) VEGF signaling, mTOR complexes, and the endoplasmic reticulum: Towards a role of metabolic sensing in the regulation of angiogenesis Mol Cell Oncol. [Abstract],
  • 2013
  • Kyrkou A, Soufi M, Bahtz R, Ferguson C, Bai M, Parton RG, Hoffmann I, Zerial M, Fotsis T, Murphy C. (2013) The RhoD to centrosomal duplication Small GTPases. [Abstract],
  • Kostaras E, Sflomos G, Pedersen NM, Stenmark H, Fotsis T, Murphy C. (2013) SARA and RNF11 interact with each other and ESCRT-0 core proteins and regulate degradative EGFR trafficking Oncogene. [Abstract],
  • Bellou S, Pentheroudakis G, Murphy C, Fotsis T. (2013) Anti-angiogenesis in cancer therapy: Hercules and hydra Cancer Lett. [Abstract],
  • Kyrkou A, Soufi M, Bahtz R, Ferguson C, Bai M, Parton RG, Hoffmann I, Zerial M, Fotsis T, Murphy C. (2013) RhoD participates in the regulation of cell-cycle progression and centrosome duplication Oncogene. [Abstract],
  • 2012
  • Bellou S, Karali E, Bagli E, Al-Maharik N, Morbidelli L, Ziche M, Adlercreutz H, Murphy C, Fotsis T (2012) The isoflavone metabolite 6-methoxyequol inhibits angiogenesis and suppresses tumor growth Mol Cancer https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406996/,
  • Bellou S, Karali E, Bagli E, Al-Maharik N, Morbidelli L, Ziche M, Adlercreutz H, Murphy C, Fotsis T. (2012) The isoflavone metabolite 6-methoxyequol inhibits angiogenesis and suppresses tumor growth Mol Cancer. [Abstract],
  • Stoyianni A, Goussia A, Pentheroudakis G, Siozopoulou V, Ioachim E, Krikelis D, Golfinopoulos V, Cervantes A, Bobos M, Fotsis T, Bellou S, Fountzilas G, Malamou-Mitsi V, Pavlidis N. (2012) Immunohistochemical study of the epithelial-mesenchymal transition phenotype in cancer of unknown primary: incidence, correlations and prognostic utility Anticancer Res. [Abstract],
  • 2011
  • Sflomos G, Kostaras E, Panopoulou E, Pappas N, Kyrkou A, Politou AS, Fotsis T, Murphy C. (2011) ERBIN is a new SARA-interacting protein: competition between SARA and SMAD2 and SMAD3 for binding to ERBIN J Cell Sci. [Abstract],
  • 2010
  • Moumtzi SS, Roberts ML, Joyce T, Evangelidou M, Probert L, Frillingos S, Fotsis T, Pintzas A. (2010) Gene expression profile associated with oncogenic ras-induced senescence, cell death, and transforming properties in human cells Cancer Invest. [Abstract],
  • 2009
  • Bellou S, Hink MA, Bagli E, Panopoulou E, Bastiaens PI, Murphy C, Fotsis T. (2009) VEGF autoregulates its proliferative and migratory ERK1/2 and p38 cascades by enhancing the expression of DUSP1 and DUSP5 phosphatases in endothelial cells Am J Physiol Cell Physiol. [Abstract],
  • Kardassis D, Murphy C, Fotsis T, Moustakas A, Stournaras C. (2009) Control of transforming growth factor beta signal transduction by small GTPases FEBS J. [Abstract],
  • Goulas V, Exarchou V, Troganis AN, Psomiadou E, Fotsis T, Briasoulis E, Gerothanassis IP. (2009) Phytochemicals in olive-leaf extracts and their antiproliferative activity against cancer and endothelial cells Mol Nutr Food Res. [Abstract],
  • 2005
  • Karavasilis V, Malamou-Mitsi V, Briasoulis E, Tsanou E, Kitsou E, Kalofonos H, Fountzilas G, Fotsis T, Pavlidis N. (2005) Matrix metalloproteinases in carcinoma of unknown primary Cancer. [Abstract],
  • Panopoulou E, Murphy C, Rasmussen H, Bagli E, Rofstad EK, Fotsis T. (2005) Activin A suppresses neuroblastoma xenograft tumor growth via antimitotic and antiangiogenic mechanisms Cancer Res. [Abstract],
  • Karavasilis V, Malamou-Mitsi V, Briasoulis E, Tsanou E, Kitsou E, Kalofonos H, Fountzilas G, Fotsis T, Pavlidis N. (2005) Angiogenesis in cancer of unknown primary: clinicopathological study of CD34, VEGF and TSP-1 BMC Cancer. [Abstract],
  • 2004
  • Adlercreutz H, Kiuru P, Rasku S, Wähälä K, Fotsis T. (2004) An isotope dilution gas chromatographic-mass spectrometric method for the simultaneous assay of estrogens and phytoestrogens in urine J Steroid Biochem Mol Biol. [Abstract],
  • Bagli E, Stefaniotou M, Morbidelli L, Ziche M, Psillas K, Murphy C, Fotsis T. (2004) Luteolin inhibits vascular endothelial growth factor-induced angiogenesis; inhibition of endothelial cell survival and proliferation by targeting phosphatidylinositol 3'-kinase activity Cancer Res. [Abstract],
  • Bagli E, Xagorari A, Papetropoulos A, Murphy C, Fotsis T. (2004) Angiogenesis in inflammation Autoimmun Rev. [Abstract],
  • Roussou I, Lambropoulos I, Pagoulatos GN, Fotsis T, Roussis IG. (2004) Decrease of heat shock protein levels and cell populations by wine phenolic extracts J Agric Food Chem. [Abstract],
  • 2002
  • Hatzi E, Murphy C, Zoephel A, Ahorn H, Tontsch U, Bamberger AM, Yamauchi-Takihara K, Schweigerer L, Fotsis T. (2002) N-myc oncogene overexpression down-regulates leukemia inhibitory factor in neuroblastoma Eur J Biochem. [Abstract],
  • Hatzi E, Murphy C, Zoephel A, Rasmussen H, Morbidelli L, Ahorn H, Kunisada K, Tontsch U, Klenk M, Yamauchi-Takihara K, Ziche M, Rofstad EK, Schweigerer L, Fotsis T. (2002) N-myc oncogene overexpression down-regulates IL-6; evidence that IL-6 inhibits angiogenesis and suppresses neuroblastoma tumor growth Oncogene. [Abstract],
  • Kotanidou A, Xagorari A, Bagli E, Kitsanta P, Fotsis T, Papapetropoulos A, Roussos C. (2002) Luteolin reduces lipopolysaccharide-induced lethal toxicity and expression of proinflammatory molecules in mice Am J Respir Crit Care Med. [Abstract],
  • Panopoulou E, Gillooly DJ, Wrana JL, Zerial M, Stenmark H, Murphy C, Fotsis T. (2002) Early endosomal regulation of Smad-dependent signaling in endothelial cells J Biol Chem. [Abstract],
  • 2001
  • Murphy C, Saffrich R, Olivo-Marin JC, Giner A, Ansorge W, Fotsis T, Zerial M. (2001) Dual function of rhoD in vesicular movement and cell motility Eur J Cell Biol. [Abstract],
  • 2000
  • Breit S, Ashman K, Wilting J, Rössler J, Hatzi E, Fotsis T, Schweigerer L. (2000) The N-myc oncogene in human neuroblastoma cells: down-regulation of an angiogenesis inhibitor identified as activin A Cancer Res. [Abstract],
  • Hatzi E, Breit S, Zoephel A, Ashman K, Tontsch U, Ahorn H, Murphy C, Schweigerer L, Fotsis T. (2000) MYCN oncogene and angiogenesis: down-regulation of endothelial growth inhibitors in human neuroblastoma cells. Purification, structural, and functional characterization Adv Exp Med Biol. [Abstract],
  • Breit S, Rössler J, Fotsis T, Schweigerer L. (2000) N-myc down-regulates activin A Biochem Biophys Res Commun. [Abstract],
  • 1999
  • Fotsis T, Breit S, Lutz W, Rössler J, Hatzi E, Schwab M, Schweigerer L. (1999) Down-regulation of endothelial cell growth inhibitors by enhanced MYCN oncogene expression in human neuroblastoma cells Eur J Biochem. [Abstract],
  • Gong H, Zölzer F, von Recklinghausen G, Rössler J, Breit S, Havers W, Fotsis T, Schweigerer L. (1999) Arginine deiminase inhibits cell proliferation by arresting cell cycle and inducing apoptosis Biochem Biophys Res Commun. [Abstract],
  • Pappa A, Seferiadis K, Fotsis T, Shevchenko A, Marselos M, Tsolas O, Messinis IE. (1999) Purification of a candidate gonadotrophin surge attenuating factor from human follicular fluid Hum Reprod. [Abstract],
  • 1998
  • Adlercreutz, H., and Fotsis, T. (1998) Comment on altered hydroxylation of estrogen in patients with postmenopausal osteopenia. J. Clin. Endocrinol. Metab. ,
  • Fotsis T, Pepper MS, Montesano R, Aktas E, Breit S, Schweigerer L, Rasku S, Wähälä K, Adlercreutz H. (1998) Phytoestrogens and inhibition of angiogenesis Baillieres Clin Endocrinol Metab. [Abstract],
  • 1997
  • Kruse, F.T., Joussen, A.M., Fotsis, T., Schweigerer, L., Rohrschneider, K., Volcker, H.E. (1997) Inhibition of neovascularization of the eye by dietary factors exemplified by isoflavonopids. Ophthalmologe ,
  • Fotsis, T., Pepper, M.S., Aktas, E., Breit, S., Rasku, S., Adlercreutz, H., Wähälä, K., Montesano, R., and Schweigerer, L. (1997) Flavonoids, dietary-derived inhibitors of cell proliferation and in vitro angiogenesis. Cancer Research ,
  • 1996
  • Wilm, M., Shevchenko, A., Houthaeve, T., Breit, S., Schweigerer, L., Fotsis, T., and Mann, M. (1996) Femtomole sequencing of proteins from polyacrylamide gels by nano-electrospray mass spectrometry. Nature ,
  • Mazur, W., Fotsis, T., Wähälä, K, Ohjala, S., Salakka, A., and Adlercreutz, H. (1996) Isotope dilute gas chromatographic-mass spectrometric method for the determination of isoflavonoids, coumestrol, and lignans in food samples. Analytical Biochemistry ,
  • Mazur, W., Fotsis, T., Wähälä, K, Ohjala, S., Salakka, A., and Adlercreutz, H. (1996) Isotope dilute gas chromatographic-mass spectrometric method for the determination of isoflavonoids, coumestrol, and lignans in food samples. Analytical Biochemistry ,
  • 1995
  • Pipili-Synetos, E., Papageorgiou, A., Sakkoula, E., Sotiropoulou, G., Fotsis, T., Karakiulakis, G., and Maragoudakis, M.E. (1995) Inhibition of angiogenesis, tumour growth and metastasis by the NO-releasing vasodilators, isosorbide mononitrate and dinitrate. Br. J. Pharmacol. ,
  • Pipili-Synetos, E., Papageorgiou, A., Sakkoula, E., Sotiropoulou, G., Fotsis, T., Karakiulakis, G., and Maragoudakis, M.E. (1995) Inhibition of angiogenesis, tumour growth and metastasis by the NO-releasing vasodilators, isosorbide mononitrate and dinitrate. Br. J. Pharmacol. ,
  • Lonning, P.E., Helle, S-I., Johannessen, D.C., Adlerctreutz, H., Lien, E.A., Tally, M., Ekse, D., Fotsis, T., Anker, G.B., and Hall, K. (1995) Relations between sex hormones, sex hormone binding globulin, insulin-like growth factor-1 and insulin-like growth factor binding protein-1 in post-menopausal breasr cancer patients. Clinical Endocrinology ,
  • Lonning, P.E., Johannessen, D.C., Lien, E.A., Ekse, D., Fotsis, T., and Adlercreutz, H. (1995) Influence of tamoxifen on sex hormones, gonadotrophins and sex hormone binding globulin in postmenopausal brease cancer patients. J. Steroid Biochem. Mol. Biol. ,
  • Fotsis, T., Pepper, M., Adlercreutz, H., Hase, T., Montesano, R., and Schweigerer, L. (1995) Genistein, a dietary ingested isoflavonoid, inhibits cell proliferation and in vitro angiogenesis. J. Nutr. ,
  • Adlercreutz, H.T., Goldin, B.R., Gorbach, S.L., Höckerstedt, K.A.V., Watanabe, S., Hämäläinen, E.K., Markkanen, M.H., Mäkelä, T.H., Wähälä, K.T., Hase, T.A. and Fotsis, T. (1995) Soybean phytoestrogen intake and cancer risk. J. Nutr. ,
  • Adlercreutz, H., Fotsis, T., Kurzer,M., Wähälä, K., Mäkelä,T., and Hase, T. (1995) Isotope dilution gas chromatographic-mass spectrometric method for the determination of unconjugated lignans and isoflavonoids in human feces, with preliminary results in omnivorous and vegetarian women. Analytical Biochemistry ,
  • Adlercreutz,H., van der Wildt, J., Kinzel, J., Attala, H., Wähälä, K., Mäkelä,T., Hase, T., and Fotsis, T. (1995) Lignan and isoflavonoid conjugates in human urine J. Steroid Biochem. Mol. Biol. ,
  • 1994
  • Adlercreutz, H., Fotsis, T., Watanabe, S., Lampe, J.,Wähälä, K., Mäkelä,T., and Hase, T. (1994) Determination of lignans and isoflavonoids in plasma by isotope dilution gas chromatograohy-mass spectrometry. Cancer Detection and Prevention ,
  • Adlercreutz,H., Gorbach,S.L., Goldin, B.R., Woods, M.N., Dwyer, J.T., Höckerstedt, K.A.V., Wähälä, K.T., Hase, T., Hämäläinen, E.K., and Fotsis, T. (1994) Diet and urinary profile in various populations. A preliminary report. Polycyclic Aromatic Compounds ,
  • Fotsis, T., Zhang, Y., Pepper, M.S., Adlercreutz, H., Montesano, R., Nawroth, P.P., and Schweigerer, L. (1994) The endogenous oestrogen metabolite 2-methoxyestradiol inhibits angiogenesis and suppresses tumour growth. Nature ,
  • 1993
  • Johannessen, G. C, Adlerceutz, H., Fotsis, T., and Lonning, E. (1993) Plasma and urinary oestrogens in breast cancer patients on treatmnet with 4-hydroxyandrostenedione. Brit. J. Cancer ,
  • Adlercreutz, H., Fotsis, T., Lampe, J., Wähälä, K., Mäkelä, T., Brunow, G., and Hase, T. (1993) Quantitative determination of lignans and isoflavonoids in plasma of omnivorous and vegetarian women by isotope dilution gas chromatography-mass spectrometry. Scand. J. Clin. Lab. Invest. ,
  • Fotsis, T., Pepper, M., Adlercreutz, H., Fleischmann, G., Hase, T., Montesano, R. and Schweigerer, L. (1993) Genistein, a dietary-derived inhibitor of in vitro angiogenesis. Proc. Natl. Acad. Sci. ,
  • 1992
  • Schweigerer, L., Christeleit, K., Fleischmann, G., Adlercreutz, H., Wähälä, K., Hase, T., Schwab, M., Ludwig, R., and Fotsis, T. (1992) Identification in human urine of a natural growth inhibitor for cells derived from solid pediatric tumours. Eur. J. Clin. Invest. ,
  • Schweigerer, L., and Fotsis, T. (1992) Angiogenesis and angiogenesis inhibitors in pediatric diseases. Eur. J. Pediatr. ,
  • 1991
  • Schweigerer. L., and Fotsis, T. (1991) Erhöhte Expression des MYCN Ongogens in humanen Neuroblastomzellen und mögliche, neue Therapie-Ansätze. Klin. Pädiatr. ,
  • Adlercreutz, H., Honjo, H., Higashi, A., Fotsis, T., Hämäläinen, E., Hasegawa, T., and Okada, H. (1991) Urinary excretion of lignans and isoflavonoid phytoestrogens in Japanese men and women consuming a traditional Japanese diet. Am. J. Clin. Nutr. ,
  • Adlercreutz, H., Fotsis, T., Bannwart, C., Wähälä, K., Brunow, G., and Hase, T. (1991) Isotope dilution gas chromatographic-mass spectrometric method for the determination of lignans and isoflavonoids in human urine, including identification of genistein. Clin. Chem. Acta. ,
  • Hämäläinen, E.,Fotsis, T., and Adlercreutz, H. (1991) A gas chromatographic method for the determination of neutral profiles in urine, including studies on the effect of oxytetracycline administration on these men. Clin. Chim. Acta ,
  • 1990
  • Schweigerer, L., Scheurich, P., and Fotsis, T. (1990) Enhanced MYCN oncogene expression in human neuroblastoma cells results in increased susceptibility to growth inhibition by TNFa. Biochem. Biophys. Res. Commun. ,
  • Fotsis, T., Murphy, C., and Gannon, F. (1990) Nucleotide sequence of the bovine insulin-like growth factor I (IGF-I) and its IGF-IA precursor. Nucl. Acids Res. ,
  • 1989
  • Adlercreutz, H., Fotsis, T., Höckerstedt, K., Hämäläinen, E., Bannwart, C., Bloigu, S., Valtonen, A., and Ollus (1989) Diet and urinary estrogen profile in premenopausal omnivorous and vegetarian women and in premenopausal women with breast cancer J. Steroid Biochem. ,
  • 1987
  • Murphy, C., Fotsis, T., Pantzar, P., Adlercreutz, H., and Martin, F. (1987) Analysis of tamoxifen, N-desmethyltamoxifen and 4-hydroxytamoxifen levels in cytosol and KCl-nuclear extracts of breast tumours from tamoxifen treated patients by gas chromatography-mass spectrometry (GC-MS) using selected ion monitoring (SIM). J. Steroid Biochem. ,
  • Murphy, C., Fotsis, T., Adlercreutz, H., and Martin, F. (1987) Analysis of tamoxifen and 4-hydroxytamoxifen levels in immature rat uterine cytoplasm and KCL-nucler extracts by gas chromatography-mass spectrometry (GC-MS) using selected ion monitoring (SIM). J. Steroid Biochem. ,
  • Fotsis, T. (1987) The multicomponent analysis of estrogens in urine by ion exchange chromatography and GC-MS -II. Fractionation and quantitation of the main groups of estrogen conjugates. J. Steroid Biochem. ,
  • Fotsis, T., and Adlercreutz, H. (1987) The multicomponent analysis of estrogens in urine by ion exchange chromatography and GC-MS -I. Quantitation of estrogens after initial hydrolysis ofconjugates. J. Steroid Biochem ,
  • Fotsis, T., Shah, H.P., Härkönen, M., and Adlercreutz, H. (1987) Fluoroenzymatic cycling assay (FECA) for the determination of catechol estrogen monomethyl ethers in human urine. Neurochemical Research ,
  • Adlercreutz, H., Höckerstedt, K., Bannwart, C., Bloigu, S.,Hämäläinen, E., Fotsis, T., and Ollus, A. (1987) Effect of dietary components, including lignans and phytoestrogens, on enterohepatic circulation and liver metabolism of estrogens and on sex hormone binding globulin (SHBG). J. Steroid Biochem. ,
  • Murphy, C., Fotsis, T., Pantzar, P., Adlercreutz, H., and Martin, F. (1987) Analysis of tamoxifen and its metabolites in human plasma by gas chromatography-mass spectrometry (GC-MS) using selected ion monitoring (SIM). J. Steroid Biochem. ,
  • 1986
  • Adlercreutz, H., Fotsis, T., Bannwart, C., Wähälä, K., Mäkelä, T., Brunow, G., and Hase, T. (1986) Determination of urinary lignans and phytoestrogen metabolites, potential antiestrogens and anticarcinogens,in urine of women on various habitual diets. J. Steroid Biochem. ,
  • Korpela, J.T., Fotsis, T., and Adlercreutz, H. (1986) Multicomponent analysis of bile acids in faeces by anion exchange and capillary column gas-liquid chromatography; application in oxytetracycline treated subjects. J. Steroid Biochem. ,
  • Adlercreutz, H., Musey, P.I., Fotsis, T., Bannwart, C.,Wähälä, K., Mäkelä, T., Brunow, G., and Hase, T. (1986) Identification of lignans and phytoestrogens in urine of chimpanzees. Clin. Chim. Acta ,
  • Adlercreutz, H., Fotsis, T, Bannwart, C., Hämäläinen, E.K.,Bloigu, S., and Ollus, A. (1986) Urinary estrogen profile determination in young Finnish vegetarian and omnivorous women. J. Steroid Biochem. ,
  • 1984
  • Bannwart, C., Adlercreutz, H., Fotsis, T., Wähälä, K., Hase, T., and Brunow, G. (1984) Identification of O-desmethylangolesin, a metabolite of daidzein, and of metairesinol, one likely plant precursor of the animal lignan enterolactone, in human urine. Finn. Chem. Lett. ,
  • Hämäläinen, E.K., Fotsis, T., and Adlercreutz, H. (1984) Rapid and reliable separation of 5a-dihydrotestosterone from testosterone on silica gel microcolumns. Clin. Chim. Acta ,
  • Bannwart, C., Fotsis, T., Heikkinen, R., and Adlercreutz,H. (1984) Identification of the isoflavonic phytoestrogen daidzeinin human urine. Clin. Chim. Acta ,
  • 1983
  • Antila, E., Fotsis, T., Wartiovaara, J., and Adlercreutz, H. (1983) Steroid metabolism in human teratocarcinoma cell line PA1. J. Steroid Biochem. ,
  • Heikkinen, R., Fotsis, T., and Adlercreutz, H. (1983) Use of ion exchange chromatography in steroid analysis. J. Steroid Biochem. ,
  • Fotsis, T., and Heikkinen, R. (1983) Selective chromatographic fractionation of catechol estrogens on anion exchangers in borate form. J. Steroid Biochem. ,
  • 1982
  • Adlercreutz, H., Fotsis, T., Heikkinen, R., Dwyer, J.T., Woods, M., Goldin, B.R., and Gorbach, S.L.. (1982) Excretion of the lignans, enterolactone and enterodiol, and of equol in omnivorous and vegetarian postmenopausal women and in breast cancer. Lancet ,
  • Fotsis, T., Heikkinen, R., Adlercreutz, H., Axelson, M., and Setchell, K.D.R. (1982) Capillary gas chromatographic method for the analysis of lignans in human urine. Clin. Chim. Acta ,
  • 1981
  • Adlercreutz, H., Fotsis, T., Heikkinen, R., Dwyer, J.T., Goldin, B.R., Gorbach, S.L., Lawson, A.M., and Setchell, K.D.R. (1981) Diet and urinary excretion of lignans in female subjects. Medical Biology ,
  • Heikkinen, R., Fotsis, T., and Adlercreutz, H. (1981) Reversed phase C18 cartridge for extraction of estrogens from urine and plasma. Clin. Chem. ,
  • Fotsis, T., Adlercreutz, H., Järvenpää, P., Setchell, K.D.R., Axelson, M., and Sjövall, J. (1981) Group separation of steroid conjugates by DEAE-Sephadex anion exchange chromatography. J. Steroid Biochem. ,
  • 1980
  • Fotsis, T., Järvenpää, P., and Adlercreutz, H. (1980) Identification of 4-hydroxyestriol in pregnancy urine. J. Clin.Endocrinol. Metab ,
  • Järvenpää, P., Kosunen, T., Fotsis, T., and Adlercreutz, H. (1980) In vitro metabolism of estrogens by isolated intestinal micro-organisms and by human fecal microflora. J. Steroid Biochem ,
  • Fotsis, T., Järvenpää, P., and Adlercreutz, H. (1980) Purification of urine for quantification of the complete estrogen profile. J. Steroid Biochem. ,
  • 1979
  • Järvenpää, P., Fotsis, T., and Adlercreutz, H. (1979) Ion exchange purification of estrogens. J. Steroid Biochem. ,
  • Adlercreutz, H., Martin, F., Järvenpää, P., and Fotsis, T (1979) Steroid adsorption and enterohepatic recycling. Contraception ,