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Research | Kleanthi Chalkiadaki
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  • 2024
  • Chalkiadaki K., Statoulla E., Zafeiri M., Voudouri G., Amvrosiadis T., Typou A., Theodoridou N., Moschovas D., Avgeropoulos A., Samiotaki M., Mason J. O. and Gkogkas CG. (2024) GABA/Glutamate neuron differentiation imbalance and increased AKT/mTOR signalling in CNTNAP2-/- cerebral organoids. bioRxiv , https://doi.org/10.1101/2024.04.21.590378
  • 2023
  • Chalkiadaki K., Statoulla E., Zafeiri M., Haji N., Lacaille J.C., Powell C.M., Jafarnejad S.M., Khoutorsky A., Gkogkas C. G. (2023) Reversal of memory and autism-related phenotypes in Tsc2+/- mice via inhibition of Nlgn1. Front Cell Dev Biol , 10.3389/fcell.2023.1205112
  • Patil S, Chalkiadaki K, Mergiya TF, Krimbacher K, Amorim IS, Akerkar S, Gkogkas CG*, Bramham CR*. (2023) eIF4E phosphorylation recruits β-catenin to mRNA cap and promotes Wnt pathway translation in dentate gyrus LTP maintenance. iScience , 10.1016/j.isci.2023.106649
  • Anadolu MN, Sun J, Kailasam S, Chalkiadaki K, Krimbacher K, Li JT, Markova T, Jafarnejad SM, Lefebvre F, Ortega J, Gkogkas CG, Sossin WS. (2023) Ribosomes in RNA Granules Are Stalled on mRNA Sequences That Are Consensus Sites for FMRP Association J Neurosci , 10.1523/JNEUROSCI.1002-22.2023
  • 2022
  • Liu D, Nanclares C, Simbriger K, Fang K, Lorsung E, Le N, Amorim IS, Chalkiadaki K, Pathak SS, Li J, Gewirtz JC, Jin VX, Kofuji P, Araque A, Orr HT, Gkogkas CG, Cao R. (2022) Autistic-like behavior and cerebellar dysfunction in Bmal1 mutant mice ameliorated by mTORC1 inhibition Mol Psychiatry. [Abstract],
  • Chalkiadaki K, Hooshmandi M, Lach G, Statoulla E, Simbriger K, Amorim IS, Kouloulia S, Zafeiri M, Pothos P, Bonneil É, Gantois I, Popic J, Kim SH, Wong C, Cao R, Komiyama NH, Atlasi Y, Jafarnejad SM, Khoutorsky A, Gkogkas CG. (2022) Mnk1/2 kinases regulate memory and autism-related behaviours via Syngap1 Brain. [Abstract],
  • 2021
  • Statoulla E, Chalkiadaki K, Karozis D, Gkogkas CG. (2021) Regulation of mRNA translation in stem cells; links to brain disorders Cell Signal. [Abstract],
  • Chalkiadaki K, Statoulla E, Markou M, Bellou S, Bagli E, Fotsis T, Murphy C, Gkogkas CG. (2021) Translational control in neurovascular brain development R Soc Open Sci. [Abstract],
  • Velli A, Iordanidou C, Asimi T, Vynichaki MI, Cholevas A, Mantouka AI, Nassens L, Chalkiadaki K, Sidiropoulou K. (2021) Sexual dimorphic effects of restraint stress on prefrontal cortical function are mediated by glucocorticoid receptor activation Eur J Neurosci. [Abstract],
  • Hooshmandi M, Truong VT, Fields E, Thomas RE, Wong C, Sharma V, Gantois I, Soriano Roque P, Chalkiadaki K, Wu N, Chakraborty A, Tahmasebi S, Prager-Khoutorsky M, Sonenberg N, Suvrathan A, Watt AJ, Gkogkas CG, Khoutorsky A. (2021) 4E-BP2-dependent translation in cerebellar Purkinje cells controls spatial memory but not autism-like behaviors Cell Rep. [Abstract],
  • 2020
  • Simbriger K, Amorim IS, Lach G, Chalkiadaki K, Kouloulia S, Jafarnejad SM, Khoutorsky A and Gkogkas C. G. (2020) Uncovering memory-related gene expression in contextual fear conditioning using ribosome profiling. Prog Neurobiol , 10.1016/j.pneurobio.2020.101903.
  • 2019
  • Kouloulia S, Hallin EI, Simbriger K, Amorim IS, Lach G, Amvrosiadis T, Chalkiadaki K, Kampaite A, Truong VT, Hooshmandi M, Jafarnejad SM, Skehel P, Kursula P, Khoutorsky A and Gkogkas C. G. (2019) Raptor-Mediated Proteasomal Degradation of Deamidated 4E-BP2 Regulates Postnatal Neuronal Translation and NF-κB Activity. Cell Rep , 10.1016/j.celrep.2019.11.023
  • Simbriger K, Amorim IS, Chalkiadaki K, Lach G, Jafarnejad SM, Khoutorsky A and Gkogkas C. G. (2019) Monitoring translation in synaptic fractions using a ribosome profiling strategy. J Neurosci Methods. , 10.1016/j.jneumeth.2019.108456
  • Chalkiadaki K, Velli A, Kyriazidis E, Stavroulaki V, Vouvoutsis V, Chatzaki E, Aivaliotis M, Sidiropoulou K. (2019) Development of the MAM model of schizophrenia in mice: Sex similarities and differences of hippocampal and prefrontal cortical function Neuropharmacology. [Abstract],
  • Papadopoulou Z, Vlaikou AM, Theodoridou D, Komini C, Chalkiadaki G, Vafeiadi M, Margetaki K, Trangas T, Turck CW, Syrrou M, Chatzi L, Filiou MD. (2019) Unraveling the Serum Metabolomic Profile of Post-partum Depression Front Neurosci. [Abstract],
  • 2018
  • Konstantoudaki X, Chalkiadaki K, Vasileiou E, Kalemaki K, Karagogeos D, Sidiropoulou K. (2018) Prefrontal cortical-specific differences in behavior and synaptic plasticity between adolescent and adult mice J Neurophysiol. [Abstract],
  • 2016
  • Konstantoudaki X, Chalkiadaki K, Tivodar S, Karagogeos D, Sidiropoulou K. (2016) Impaired synaptic plasticity in the prefrontal cortex of mice with developmentally decreased number of interneurons Neuroscience. [Abstract],
  • 2014
  • Konstantoudaki X, Papoutsi A, Chalkiadaki K, Poirazi P, Sidiropoulou K. (2014) Modulatory effects of inhibition on persistent activity in a cortical microcircuit model Front Neural Circuits. [Abstract],
  • 2003
  • Pozidis C, Chalkiadaki A, Gomez-Serrano A, Stahlberg H, Brown I, Tampakaki AP, Lustig A, Sianidis G, Politou AS, Engel A, Panopoulos NJ, Mansfield J, Pugsley AP, Karamanou S, Economou A. (2003) Type III protein translocase: HrcN is a peripheral ATPase that is activated by oligomerization J Biol Chem. [Abstract],