2024
- Vrettos EΙ, Kyrkou SG, Zoi V, Giannakopoulou M, Chatziathanasiadou MV, Kanaki Z, Agalou A, Bistas VP, Kougioumtzi A, Karampelas T, Diamantis DA, Murphy C, Beis D, Klinakis A, Tamvakopoulos C, Kyritsis AP, Alexiou GA, Tzakos AG. (2024) A Novel Fluorescent Gemcitabine Prodrug That Follows a Nucleoside Transporter-Independent Internalization and Bears Enhanced Therapeutic Efficacy With Respect to Gemcitabine. Chemistry ,
2022
- Chalmantzi V, Simitzi C, Papadopoulos A, Bagli E, Murphy C, Stratakis E, Fotsis T. (2022) Culturing Human Pluripotent Stem Cells on Micropatterned Silicon Surfaces Methods Mol Biol. [Abstract],
2021
- Papadopoulos A, Chalmantzi V, Mikhaylichenko O, Hyvönen M, Stellas D, Kanhere A, Heath J, Cunningham DL, Fotsis T, Murphy C. (2021) Combined transcriptomics and phosphoproteomic analysis of BMP4 signaling in human embryonic stem cells. Stem Cell Res. ,
- Kostopoulou N, Bellou S, Bagli E, Markou M, Kostaras E, Hyvönen M, Kalaidzidis Y, Papadopoulos A, Chalmantzi V, Kyrkou A, Panopoulou E, Fotsis T, Murphy C. (2021) Embryonic stem cells are devoid of macropinocytosis, a trafficking pathway for activin a in differentiated cells J Cell Sci. [Abstract], 10.1242/jcs.246892
- Kougioumtzi A, Chatziathanasiadou MV, Vrettos EI, Sayyad N, Sakka M, Stathopoulos P, Mantzaris MD, Ganai AM, Karpoormath R, Vartholomatos G, Tsikaris V, Lazarides T, Murphy C, Tzakos AG. (2021) Development of novel GnRH and Tat 48-60 based luminescent probes with enhanced cellular uptake and bioimaging profile Dalton Trans. [Abstract], 10.1039/D1DT00060H
- Chalkiadaki K, Statoulla E, Markou M, Bellou S, Bagli E, Fotsis T, Murphy C, Gkogkas CG. (2021) Translational control in neurovascular brain development R Soc Open Sci. [Abstract],
- Vrettos EI, Karampelas T, Sayyad N, Kougioumtzi A, Syed N, Crook T, Murphy C, Tamvakopoulos C, Tzakos AG. (2021) Development of programmable gemcitabine-GnRH pro-drugs bearing linker controllable 'click' oxime bond tethers and preclinical evaluation against prostate cancer Eur J Med Chem. [Abstract],
- Papadopoulos A, Chalmantzi V, Hyvönen M, Stellas D, Syrrou M, Fotsis T, Murphy C. (2021) Supporting data on combined transcriptomic and phosphoproteomic analysis of BMP4 signaling in human embryonic stem cells Data Brief. [Abstract],
- Markou M, Kouroupis D, Fotsis T, Bagli E, Murphy C. (2021) Basic concepts in 3D Cell Culture. Book chapter: Vascularisation in 3D Cell Culture. [Abstract], 10.1007/978-3-030-66749-8
- Vrettos E, Karampelas T., Sayyad N, Kougioumtzi A, Syed N, Crook T, Murphy C, Tamvakopoulos C, Tzakos A. (2021) Development of programmable gemcitabine-GnRH pro-drugs bearing linker controllable “click” oxime bond tethers and preclinical evaluation against prostate cancer. Eur. J. Medicinal Chem. 211 ,
- Papadopoulos A, Chalmantzi V, Mikhaylichenko O, Hyvönen M, Stellas D, Kanhere A, Heath J, Cunningham DL, Fotsis T, Murphy C (2021) upporting data on combined transcriptomics and phosphoproteomic analysis of BMP4 signaling in human embryonic stem cells. Data in Brief 35 ,
2020
- Markou M, Kouroupis D, Badounas F, Katsouras A, Kyrkou A, Fotsis T, Murphy C, Bagli E. (2020) Tissue Engineering Using Vascular Organoids From Human Pluripotent Stem Cell Derived Mural Cell Phenotypes Front Bioeng Biotechnol. [Abstract], 10.3389/fbioe.2020.00278.
- Papadopoulos A, Chalmantzi V, Mikhaylichenko O, Hyvönen M, Stellas D, Kanhere A, Heath J, Cunningham DL, Fotsis T, Murphy C. (2020) Combined transcriptomic and phosphoproteomic analysis of BMP4 signaling in human embryonic stem cells Stem Cell Res. [Abstract],
- Markou M, Kouroupis D, Badounas F, Katsouras A, Kyrkou A, Fotsis T, Murphy C, Bagli E. (2020) Tissue Engineering Using Vascular Organoids From Human Pluripotent Stem Cell Derived Mural Cell Phenotypes. Frontiers in Bioengineering and Biotechnology , 10.3389/fbioe.2020.00278
2016
- Basagiannis D, Zografou S, Murphy C, Fotsis T, Morbidelli L, Ziche M, Bleck C, Mercer J, Christoforidis S. (2016) VEGF induces signalling and angiogenesis by directing VEGFR2 internalisation through macropinocytosis J Cell Sci. [Abstract],
- Tsolis K.C., Bagli E., Kanaki K., Zografou S., Carpentier S., Bei E.S., Christoforidis S., Zervakis M., Murphy C., Fotsis T., Economou A. (2016) Proteome Changes during Transition from Human Embryonic to Vascular Progenitor Cells J Proteome Res. [Abstract], 10.1021/acs.jproteome.6b00180.
- Kyrkou A, Stellas D, Syrrou M, Klinakis A, Fotsis T, Murphy C. (2016) Generation of human induced pluripotent stem cells in defined, feeder-free conditions Stem Cell Res. [Abstract],
- Kouroupis D, Kyrkou A, Triantafyllidi E, Katsimpoulas M, Chalepakis G, Goussia A, Georgoulis A, Murphy C, Fotsis T. (2016) Generation of stem cell-based bioartificial anterior cruciate ligament (ACL) grafts for effective ACL rupture repair Stem Cell Res. [Abstract],
- Kyrkou A, Stellas D, Syrrou M, Klinakis A, Fotsis T, Murphy C (2016) Generation of human induced pluripotent stem cells in defined, feeder-free conditions. Stem Cell Research ,
- Nussbaumer M, Asara JM, Teplytska L, Murphy MP, Logan A, Turck CW, Filiou MD#. (2016) Selective mitochondrial targeting exerts anxiolytic effects in vivo. Neuropsychopharmacology ,
2014
- Karali E, Bellou S, Stellas D, Klinakis A, Murphy C, Fotsis T. (2014) VEGF Signals through ATF6 and PERK to promote endothelial cell survival and angiogenesis in the absence of ER stress Mol Cell. [Abstract],
- Kostaras E, Pedersen NM, Stenmark H, Fotsis T, Murphy C. (2014) SARA and RNF11 at the crossroads of EGFR signaling and trafficking Methods Enzymol. [Abstract],
- Karali E, Bellou S, Stellas D, Klinakis A, Murphy C, Fotsis T. (2014) VEGF signaling, mTOR complexes, and the endoplasmic reticulum: Towards a role of metabolic sensing in the regulation of angiogenesis Mol Cell Oncol. [Abstract],
2013
- Kyrkou A, Soufi M, Bahtz R, Ferguson C, Bai M, Parton RG, Hoffmann I, Zerial M, Fotsis T, Murphy C. (2013) The RhoD to centrosomal duplication Small GTPases. [Abstract],
- Kostaras E, Sflomos G, Pedersen NM, Stenmark H, Fotsis T, Murphy C. (2013) SARA and RNF11 interact with each other and ESCRT-0 core proteins and regulate degradative EGFR trafficking Oncogene. [Abstract],
- Bellou S, Pentheroudakis G, Murphy C, Fotsis T. (2013) Anti-angiogenesis in cancer therapy: Hercules and hydra Cancer Lett. [Abstract],
- Kyrkou A, Soufi M, Bahtz R, Ferguson C, Bai M, Parton RG, Hoffmann I, Zerial M, Fotsis T, Murphy C. (2013) RhoD participates in the regulation of cell-cycle progression and centrosome duplication Oncogene. [Abstract],
2012
- Bellou S, Karali E, Bagli E, Al-Maharik N, Morbidelli L, Ziche M, Adlercreutz H, Murphy C, Fotsis T (2012) The isoflavone metabolite 6-methoxyequol inhibits angiogenesis and suppresses tumor growth Mol Cancer https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406996/,
- Bellou S, Karali E, Bagli E, Al-Maharik N, Morbidelli L, Ziche M, Adlercreutz H, Murphy C, Fotsis T. (2012) The isoflavone metabolite 6-methoxyequol inhibits angiogenesis and suppresses tumor growth Mol Cancer. [Abstract],
2011
- Sflomos G, Kostaras E, Panopoulou E, Pappas N, Kyrkou A, Politou AS, Fotsis T, Murphy C. (2011) ERBIN is a new SARA-interacting protein: competition between SARA and SMAD2 and SMAD3 for binding to ERBIN J Cell Sci. [Abstract],
2009
- Bellou S, Hink MA, Bagli E, Panopoulou E, Bastiaens PI, Murphy C, Fotsis T. (2009) VEGF autoregulates its proliferative and migratory ERK1/2 and p38 cascades by enhancing the expression of DUSP1 and DUSP5 phosphatases in endothelial cells Am J Physiol Cell Physiol. [Abstract],
- Kardassis D, Murphy C, Fotsis T, Moustakas A, Stournaras C. (2009) Control of transforming growth factor beta signal transduction by small GTPases FEBS J. [Abstract],
2007
- Murphy C. (2007) Endo-fin-ally a SARA for BMP receptors J Cell Sci. [Abstract],
2006
- Fyhrquist P, Mwasumbi L, Vuorela P, Vuorela H, Hiltunen R, Murphy C, Adlercreutz H (2006) Preliminary antiproliferative effects of some species of Terminalia, Combretum and Pteleopsis collected in Tanzania on some human cancer cell lines. Fitoterapia ,
2005
- Papanikolaou A, Papafotika A, Murphy C, Papamarcaki T, Tsolas O, Drab M, Kurzchalia TV, Kasper M, Christoforidis S. (2005) Cholesterol-dependent lipid assemblies regulate the activity of the ecto-nucleotidase CD39 J Biol Chem. [Abstract],
- Panopoulou E, Murphy C, Rasmussen H, Bagli E, Rofstad EK, Fotsis T. (2005) Activin A suppresses neuroblastoma xenograft tumor growth via antimitotic and antiangiogenic mechanisms Cancer Res. [Abstract],
2004
- Bagli E, Stefaniotou M, Morbidelli L, Ziche M, Psillas K, Murphy C, Fotsis T. (2004) Luteolin inhibits vascular endothelial growth factor-induced angiogenesis; inhibition of endothelial cell survival and proliferation by targeting phosphatidylinositol 3'-kinase activity Cancer Res. [Abstract],
- Bagli E, Xagorari A, Papetropoulos A, Murphy C, Fotsis T. (2004) Angiogenesis in inflammation Autoimmun Rev. [Abstract],
2002
- Karetsou Z, Kretsovali A, Murphy C, Tsolas O, Papamarcaki T. (2002) Prothymosin alpha interacts with the CREB-binding protein and potentiates transcription EMBO Rep. [Abstract],
- Hatzi E, Murphy C, Zoephel A, Ahorn H, Tontsch U, Bamberger AM, Yamauchi-Takihara K, Schweigerer L, Fotsis T. (2002) N-myc oncogene overexpression down-regulates leukemia inhibitory factor in neuroblastoma Eur J Biochem. [Abstract],
- Hatzi E, Murphy C, Zoephel A, Rasmussen H, Morbidelli L, Ahorn H, Kunisada K, Tontsch U, Klenk M, Yamauchi-Takihara K, Ziche M, Rofstad EK, Schweigerer L, Fotsis T. (2002) N-myc oncogene overexpression down-regulates IL-6; evidence that IL-6 inhibits angiogenesis and suppresses neuroblastoma tumor growth Oncogene. [Abstract],
- Panopoulou E, Gillooly DJ, Wrana JL, Zerial M, Stenmark H, Murphy C, Fotsis T. (2002) Early endosomal regulation of Smad-dependent signaling in endothelial cells J Biol Chem. [Abstract],
2001
- Murphy C, Saffrich R, Olivo-Marin JC, Giner A, Ansorge W, Fotsis T, Zerial M. (2001) Dual function of rhoD in vesicular movement and cell motility Eur J Cell Biol. [Abstract],
2000
- Hatzi E, Breit S, Zoephel A, Ashman K, Tontsch U, Ahorn H, Murphy C, Schweigerer L, Fotsis T. (2000) MYCN oncogene and angiogenesis: down-regulation of endothelial growth inhibitors in human neuroblastoma cells. Purification, structural, and functional characterization Adv Exp Med Biol. [Abstract],
1999
- Pappas P, Stephanou P, Sotiropoulou M, Murphy C, Salminen L, Marselos M. (1999) Effects of tamoxifen and toremifene on ALDH1 and ALDH3 in human retinal pigment epithelial cells and rat liver Adv Exp Med Biol. [Abstract],
1998
- Simonsen A, Lippé R, Christoforidis S, Gaullier JM, Brech A, Callaghan J, Toh BH, Murphy C, Zerial M, Stenmark H. (1998) EEA1 links PI(3)K function to Rab5 regulation of endosome fusion Nature. [Abstract],
1990
- Fotsis, T., Murphy, C., and Gannon, F. (1990) Nucleotide sequence of the bovine insulin-like growth factor I (IGF-I) and its IGF-IA precursor. Nucl. Acids Res. ,
1987
- Murphy, C., Fotsis, T., Pantzar, P., Adlercreutz, H., and Martin, F. (1987) Analysis of tamoxifen, N-desmethyltamoxifen and 4-hydroxytamoxifen levels in cytosol and KCl-nuclear extracts of breast tumours from tamoxifen treated patients by gas chromatography-mass spectrometry (GC-MS) using selected ion monitoring (SIM). J. Steroid Biochem. ,
- Murphy, C., Fotsis, T., Adlercreutz, H., and Martin, F. (1987) Analysis of tamoxifen and 4-hydroxytamoxifen levels in immature rat uterine cytoplasm and KCL-nucler extracts by gas chromatography-mass spectrometry (GC-MS) using selected ion monitoring (SIM). J. Steroid Biochem. ,
- Murphy, C., Fotsis, T., Pantzar, P., Adlercreutz, H., and Martin, F. (1987) Analysis of tamoxifen and its metabolites in human plasma by gas chromatography-mass spectrometry (GC-MS) using selected ion monitoring (SIM). J. Steroid Biochem. ,
